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Risk prediction for long-term cardiovascular events in patients with concurrent hypertension, HFpEF, and unstable angina: a multicenter machine learning-assisted cohort study

Abstract: Patients with concurrent hypertension, heart failure with preserved ejection fraction (HFpEF), and unstable angina pectoris (UAP) represent a high-risk population with…

Date: 2026-07-23

Mixed short-chain fatty acids and high-fiber diet reshape SCFA profiles and attenuate post-infarction cardiac fibrosis in mice

Abstract: Short-chain fatty acids (SCFAs) are microbiota-derived metabolites implicated in immunometabolic regulation. How their systemic and myocardial signatures diverge during…

Date: 2026-07-23

Higher remnant cholesterol to lymphocyte ratio is associated with vulnerable plaque features in acute coronary syndrome

Abstract: Remnant cholesterol to lymphocyte ratio (RCLR) integrates atherogenic lipid metabolism and systemic inflammation, potentially reflecting plaque vulnerability in acute…

Date: 2026-07-23

Febrile neutropenia in children and adolescents with acute myeloid leukemia during induction therapy

Abstract: Febrile neutropenia (FN) is a serious and potentially life-threatening complication in children with acute myeloid leukemia (AML), particularly during induction…

Date: 2026-07-22

Avatrombopag switching from other thrombopoietic agents in severe and persistent cancer treatment-induced thrombocytopenia: a multicentre real-world study

Abstract: Severe and persistent cancer treatment-induced thrombocytopenia (CTIT) remains a major obstacle to continuation of antineoplastic therapy and faces an increased risk of…

Date: 2026-07-22

Efficacy and safety of intrathyroidal dexamethasone therapy in severe subacute thyroiditis – a real-world prospective single center study

Abstract: Clinically severe subacute thyroiditis (SAT) requires high cumulative doses of systemic steroids. The aim of the DLISAT study was to assess efficacy and safety of…

Date: 2026-07-22

Thyroid follicular cell-derived GDF15 attenuates inflammation and lipid dysregulation in Hashimoto's thyroiditis

Abstract: Hashimoto's thyroiditis (HT) is a prevalent autoimmune thyroid disorder, typically triggers localized thyroid inflammation and systemic dyslipidemia, and progression to…

Date: 2026-07-22

Association between inflammatory indicators derived from preconception complete blood count and specific adverse fetal, neonatal, and pregnancy outcomes: a national cohort study

Abstract: Adverse fetal and neonatal outcomes, including small for gestational age (SGA), large for gestational age (LGA), and low birth weight (LBW), seriously endanger maternal…

Date: 2026-07-22

Associations of dietary quality and physical activity with glycemic control in patients with type 2 diabetes: the moderating role of trait mindfulness

Abstract: Dietary quality and physical activity are fundamental components of glycemic management in patients with type 2 diabetes mellitus (T2DM). However, glycemic responses to…

Date: 2026-07-22

Association of continuous glucose monitoring metrics with early diabetic kidney disease in early-onset type 2 diabetes

Abstract: The rising prevalence of early-onset type 2 diabetes (T2DM) has become a major public health concern, with these patients facing a particularly high risk of early…

Date: 2026-07-22