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Outcomes and predictors of second haploidentical hematopoietic stem cell transplantation for pediatric acute leukemia relapsing after a first allograft

Abstract: The clinical efficacy and prognostic factors of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) as a salvage approach for children with relapsed…

Date: 2026-07-20

Explainable machine learning for osteoporosis detection in patients with osteopenia: model development and validation using routine clinical data from an Asian cohort

Abstract: Osteopenia is a critical precursor to osteoporosis (OP), yet accurately discriminating OP from osteopenia among individuals with low bone mass remains challenging. While…

Date: 2026-07-20

Micromegaly: a distinct clinical entity? Insights from a monocentric cohort study

Abstract: The term “micromegaly” historically refers to patients with acromegalic features, elevated IGF-1, but normal growth hormone (GH) levels. The physiological mechanism, the…

Date: 2026-07-20

IgE levels correlate with Fc ? RI expression on circulatory basophils but not with their activation response in patients with Hymenoptera anaphylaxis

Abstract: Measurement of IgE levels, skin prick tests (SPT), and basophil activation tests (BAT) are the gold standards for diagnosing Hymenoptera allergy. Currently, BAT most…

Date: 2026-07-20

RAG1 deficiency durably alters dermal group 2 innate lymphoid cells and modifies contact hypersensitivity

Abstract: Dermal group 2 innate lymphoid cells (dILC2s) contribute to skin homeostasis and inflammatory responses, yet they are frequently studied in Rag1-deficient mice in which…

Date: 2026-07-20

Risk factors and a nomogram for predicting severe acute kidney injury in pediatric sepsis: a retrospective study

Abstract: To develop and validate a nomogram for predicting the risk of severe acute kidney injury (AKI) in children with sepsis. A total of 987 children with sepsis admitted to…

Date: 2026-07-20

Gram-negative bloodstream infections in pediatric patients: antimicrobial resistance and factors associated with mortality

Abstract: Gram-negative bloodstream infections (BSIs) are associated with substantial morbidity and mortality in pediatric patients, particularly among critically ill children.…

Date: 2026-07-20

Association of serum growth differentiation factor 11 with asthma severity, inflammation, and airway remodeling in pediatric patients

Abstract: Growth differentiation factor 11 (GDF11), a member of the transforming growth factor beta (TGF- ? ) superfamily, is implicated in tissue remodeling and inflammation.…

Date: 2026-07-20

Integrated cardiac, endocrine, and genetic assessment in adolescent basketball players

Abstract: Athletes pursuing a professional basketball career are routinely evaluated by sports physicians using laboratory testing, electrocardiography, and exercise stress…

Date: 2026-07-20

IgA anti-?2-glycoprotein I as an independent risk factor in acute venous thromboembolism

Abstract: Venous thromboembolism (VTE) is the third most common cause of cardiovascular death. Primary Antiphospholipid Syndrome (P-APS) is a chronic systemic autoimmune disorder…

Date: 2026-07-20