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Association between peripheral blood T cell subsets and clinical disability in multiple sclerosis patients

Abstract: Multiple sclerosis (MS) is a chronic immune-mediated disorder involving complex interactions among adaptive and innate immune pathways. The relationship between…

Date: 2026-07-20

Risk assessment of acute heart failure after endovascular therapy in acute ischemic stroke: a nomogram-based study

Abstract: Acute heart failure (AHF) is a life-threatening complication following endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO). This…

Date: 2026-07-20

Inflammation, oxidative stress, matrix metalloproteinases and DNA damage in diabetic polyneuropathy and neuropathic pain

Abstract: Diabetic polyneuropathy is one of the most common complications of type 2 diabetes mellitus (DM) and represents a major cause of morbidity and impaired quality of life.…

Date: 2026-07-20

Pneumococcal transmission is driven by TNFR2+ regulatory T-cells

Abstract: Pneumococcal serotype 1 (sequence type 217) is a leading cause of invasive disease outbreaks in Sub-Saharan Africa, causing significant morbidity and mortality.…

Date: 2026-07-20

CCR1-mediated monocyte chemotaxis in the immunopathology of primary Sjögren’s syndrome: multi-omics integration analysis and computational target prioritization implicating Polygonatum odoratum

Abstract: Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease with no specific etiological treatment. Polygonatum odoratum , a traditional yin-nourishing…

Date: 2026-07-20

Treatment patterns and survival outcomes in elderly patients with intrahepatic cholangiocarcinoma: NCDB analysis

Abstract: Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with a poor prognosis and rising incidence that is most commonly diagnosed in older adults. However, elderly…

Date: 2026-07-20

Predicting patient-specific quality assurance outcomes in helical tomotherapy using plan complexity and 3D dose-distribution radiomics

Abstract: Pretreatment patient-specific quality assurance (PSQA) for helical tomotherapy (HT) is time-consuming and resource-intensive. Machine-learning-based screening tools may…

Date: 2026-07-20

Treatment patterns and outcomes of patients with a diagnosis of metastatic pancreatic adenocarcinoma in the United States, 2019–2024

Abstract: Approximately half of patients with pancreatic cancer present with metastatic disease at diagnosis, for whom 5?year survival remains ~3%. This retrospective study…

Date: 2026-07-20

Stereotactic versus hippocampal avoidance whole-brain radiotherapy combined with immune checkpoint inhibitors for multiple brain metastases in non-small cell lung cancer: a multi-center retrospective study

Abstract: The optimal radiotherapy (RT) approach combined with immune checkpoint inhibitors (ICIs) for non-small cell lung cancer (NSCLC) patients with multiple brain metastases…

Date: 2026-07-20

Foundation model-enhanced multimodal radiomics for predicting response to chemo-immunotherapy in advanced lung squamous cell carcinoma

Abstract: To develop and validate a foundation model–driven multimodal fusion framework for non-invasive prediction of treatment response to first-line chemo-immunotherapy in…

Date: 2026-07-20