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Blood urea nitrogen to albumin ratio and 1-year mortality after hip fracture surgery in older adults: a retrospective cohort study

Abstract: Hip fracture (HF) is a fragility fracture associated with a high risk of death in older adults. The blood urea nitrogen to albumin ratio (BAR) may reflect renal function…

Date: 2026-07-17

Vedolizumab in biologic-naïve ulcerative colitis: a multicenter real-world evaluation of clinical benefits and exploratory inflammatory indices

Abstract: Although vedolizumab (VDZ) serves as a primary biologic for ulcerative colitis (UC), long-term data in Chinese biologic-naïve cohorts and cost-effective prognostic…

Date: 2026-07-17

Development and validation of a novel prognostic score for HBV-related acute-on-chronic liver failure

Abstract: Acute-on-chronic liver failure patients have high short-term mortality rates, and HBV infection is the most common cause. Current prognostic models for HBV-ACLF patients…

Date: 2026-07-17

Imaging patterns of hemorrhagic transformation after tenecteplase versus alteplase in real-world practice

Abstract: While randomized trials have demonstrated noninferiority of tenecteplase compared with alteplase in terms of functional outcomes and symptomatic intracranial hemorrhage…

Date: 2026-07-17

Psychoneuroimmunological changes in adults with obesity receiving chiropractic care: a single-arm pilot trial

Abstract: Psychoneuroimmunology (PNI) is an interdisciplinary framework that merges psychology, neurology, and immunology. Obesity, a condition of increasing global prevalence, is…

Date: 2026-07-17

CCL25 chemokine promotes antiviral tissue resident CD4 + and CD8 + effector memory T RM cells associated with a reduction of ocular herpes infection and disease: a potential gut–eye axis in herpes immunity

Abstract: CCL25, a mucosal chemokine mainly produced in the gut, is known for its role in intestinal immunity through CCR9. In this study, we tested whether CCL25 also contributes…

Date: 2026-07-17

Pentraxin-3 in thyroid nodules: a systemic marker of pathology and a local mediator of inflammation and carcinoma

Abstract: Thyroid nodules are extremely common, yet the exact physio-pathological mechanisms underlying their benign or malignant development remain poorly understood. Pentraxin-3…

Date: 2026-07-17

Microstructural alterations in brain tissue of ME/CFS and long COVID using diffusion tensor imaging and diffusion kurtosis imaging

Abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long COVID have overlapping symptoms, such as profound fatigue, cognitive impairment, post-exertional…

Date: 2026-07-17

Biomarker patterns across skin–lung–gut burden in systemic sclerosis

Abstract: Systemic sclerosis (SSc) is a multisystem autoimmune disease in which skin, lung, and gastrointestinal involvement often co-occur. Whether increasing organ…

Date: 2026-07-17

Characterization of cancer-associated fibroblast populations that promote tertiary lymphoid structure formation in murine melanoma tumors

Abstract: In recent years, the clinical relevance of tertiary lymphoid structures (TLS) in cancer has become increasingly clear. However, the mechanisms that promote TLS…

Date: 2026-07-17