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EQD2-adjusted mean lung dose and symptomatic pneumonitis after thoracic radiotherapy following immune checkpoint inhibitors in lung cancer: a single-center retrospective cohort study

Abstract: Evidence on pneumonitis after thoracic radiotherapy following immune checkpoint inhibitor (ICI) exposure remains limited. We examined associations with voxel-wise EQD2…

Date: 2026-10-09

Risk factors for aortic disease combined with coronary artery disease and the significance of preoperative coronary assessment in endovascular aortic repair

Abstract: The clinical utility of preoperative coronary assessment in patients undergoing endovascular aortic repair (EVAR) remains uncertain. This study aims to identify risk…

Date: 2026-10-09

Early changes in CT-derived quantitative flow ratio after transcatheter aortic valve replacement: a serial coronary physiological assessment

Abstract: Transcatheter aortic valve replacement (TAVR) is an established treatment for severe aortic valve stenosis, but its effects on coronary physiology remain incompletely…

Date: 2026-10-09

Prognostic value of the inflammatory burden index in predicting 1-year mortality in patients undergoing cardiac resynchronization therapy for heart failure

Abstract: Heart failure (HF) is one of the leading causes of death and impairs quality of life worldwide. Systemic inflammation has been increasingly recognized as a major…

Date: 2026-10-09

Cross-scale genetic, molecular, and cellular triangulation prioritizes ACSL5 as a T3-responsive candidate linking hypothyroidism liability to anemia

Abstract: Anemia is a recognized complication of hypothyroidism, but disease-level genetic studies have not identified a clear erythroid cell-intrinsic target. We integrated…

Date: 2026-10-08

Associations between a series of composite glucose-lipid indices and moderately increased albuminuria in patients with type 2 diabetes mellitus: a cross-sectional study

Abstract: Diabetic kidney disease (DKD) represents one of the most significant microvascular complications associated with type 2 diabetes mellitus (T2DM). Moderately increased…

Date: 2026-10-08

Mortality and clinical outcomes in preterm infants with patent ductus arteriosus according to pharmacological treatment or expectant management: a retrospective cohort study

Abstract: Patent ductus arteriosus (PDA) is frequent in preterm newborns and its management remains controversial. The objective was to evaluate the association between…

Date: 2026-10-08

Comparison of an automated and paper bladder diary in pediatric patients: mixed-methods, randomized crossover study

Abstract: Bladder diaries are recommended for assessing pediatric lower urinary tract symptoms, but paper diaries require manual measurement, recording, and interpretation.…

Date: 2026-10-08

Coordinated transcriptional and epigenetic regulation of type 2 CD8 + T cells in asthma

Abstract: Steroid-insensitive type 2 cytokine-producing CD8 + T cells (Tc2) are enriched in patients with severe asthma and correlate with disease severity, highlighting their…

Date: 2026-10-08

Usability of digital medicine systems in patients with schizophrenia or schizoaffective disorder

Abstract: To assess the usability and performance of digital medication management systems (DMS) for patients with stable ambulatory schizophrenia and schizoaffective disorder.…

Date: 2026-10-08