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Higher abundance of micro- and nanoplastics in inflammatory tissues from patients with intestinal erosion

Abstract: The detrimental effects of micro- and nanoplastics (MNPs) on human health have been the subject of intense research in recent years, but there is little data on how MNPs…

Date: 2026-07-10

Dietary background, serum polyunsaturated fatty acid profiles, and 1-year outcomes after large-artery atherosclerotic stroke: a multicenter cohort study

Abstract: To examine whether long-term dietary background is associated with post-stroke outcomes in patients with large-artery atherosclerotic cerebral infarction (LAA-CI), and…

Date: 2026-07-10

Clinical outcomes and bleeding events associated with tirofiban combined with intravenous alteplase in acute ischaemic stroke: a retrospective single-center study

Abstract: To evaluate the clinical efficacy and bleeding risk of tirofiban combined with intravenous alteplase in patients with acute ischaemic stroke (AIS). This retrospective…

Date: 2026-07-10

Potential neuroprotective and anticonvulsant effects of Ganoderma lucidum ethanol extract and its impact on affective comorbidities associated with pentylenetetrazol kindling model of epilepsy: behavioral, biochemical and histological studies

Abstract: Epilepsy is a chronic neurological disorder that is strongly influenced by oxidative stress and neuronal death, two major pathophysiological factors. According to…

Date: 2026-07-10

Real-world evidence of baseline soluble CD25 as a prognostic biomarker and indicator of differential EGFR–TKI benefit in stage IV lung adenocarcinoma

Abstract: Outcomes in stage IV lung adenocarcinoma (LUAD) remain heterogeneous despite established genomic and immune biomarkers. We evaluated the prognostic and predictive value…

Date: 2026-07-10

Berberine restrains the expansion of colorectal cancer organoids by blocking cell cycle progression and reducing lipid synthesis

Abstract: Among all the most prevalent malignant gastrointestinal cancers, colorectal cancer (CRC) occurs frequently in all the populations around the world. Despite remarkable…

Date: 2026-07-10

Machine learning-based prognostic model for triple-negative breast cancer with axillary lymph node metastasis

Abstract: Triple-negative breast cancer (TNBC) with axillary lymph node metastasis (ALNM) represents a high-risk population with substantially worse prognosis compared to other…

Date: 2026-07-10

Role of homocysteine, vitamins B12, B6, B1, and folate in Saudi patients with premature acute coronary syndrome

Abstract: Homocysteine (HCY) has been implicated in cardiovascular disease through adverse effects on vascular endothelium, oxidative stress, and thrombogenic pathways. Saudi…

Date: 2026-07-10

Flow-based imaging reveals dissociated monocyte adhesion and transmigration patterns between TNF-? and diabetes-induced vascular inflammation

Abstract: Monocyte–endothelial interactions drive both acute inflammation and chronic vascular disease in type 2 diabetes mellitus (T2DM), yet whether TNF-?–induced and…

Date: 2026-07-10

Association of triglyceride glucose index with cardiovascular autonomic neuropathy in type 2 diabetes mellitus

Abstract: Cardiovascular autonomic neuropathy (CAN), defined as impaired autonomic control of the cardiovascular system, is a highly prevalent yet frequently underdiagnosed…

Date: 2026-07-09