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Preoperative risk score for malignancy in Bethesda III thyroid nodules: a multicentre retrospective study

Abstract: Bethesda III thyroid nodules represent a heterogeneous cytological category with an estimated malignancy risk of 13–30%, creating uncertainty in clinical…

Date: 2026-07-06

Effectiveness and safety of switching biologics after secukinumab treatment failure in moderate-to-severe plaque psoriasis: a retrospective cohort study

Abstract: Biologic switching is common in clinical practice for patients with moderate-to-severe plaque psoriasis who fail secukinumab therapy. There is limited real-world…

Date: 2026-07-06

Assessment of growth and pain trajectories for children and adolescents receiving chemotherapy for acute lymphoblastic leukemia in Northern Thailand using group-based trajectory modeling

Abstract: Children with leukemia often experience growth and symptom changes during treatment. Our aim was to examine bodyweight, body mass index (BMI) and pain trajectories,…

Date: 2026-07-06

Association between the unaccompanied nursing care model and postoperative delirium in older adults with hip fractures: a retrospective before-and-after cohort study

Abstract: Reduced family participation and restricted visitation have been shown to increase the risk of delirium in older adults. The unaccompanied nursing care model (UNCM),…

Date: 2026-07-06

Evaluation of the effectiveness of the model of family participatory care based on cloud follow-up in enhancing the quality of life and psychological well-being of patients with chronic difficult-to-heal traumatic tumours

Abstract: Patients with chronic difficult-to-heal traumatic tumours are prone to comorbid anxiety and depression. The clinical application of the cloud-based family engagement…

Date: 2026-07-06

Synergistic associations between dietary patterns, lifestyle behaviors and childhood obesity

Abstract: To analyze the relationships between diet, lifestyle behaviors and obesity among preschool children aged 3–7 in Wuxi City, providing a scientific basis for implementing…

Date: 2026-07-06

Perinatal morphine exposure induces chromatin and transcriptomic remodeling to alter immune and metabolic function

Abstract: Infants exposed to opioids in utero are at risk of developing Neonatal Opioid Withdrawal Syndrome (NOWS). Rodent models of perinatal opioid exposure can reliably…

Date: 2026-07-06

Epidemiological investigation of adolescent idiopathic scoliosis and evaluation of the therapeutic effect of an integrated sports and medicine rehabilitation strategy for scoliosis treatment

Abstract: Adolescent idiopathic scoliosis (AIS) is a common spinal deformity with significant health impacts. This study aimed to investigate the epidemiology of AIS in a Chinese…

Date: 2026-07-06

Exploring the predictive capacity of smartphone-based digital phenotyping to monitor pain and physical quality of life in advanced cancer patients, family caregivers, and dyads

Abstract: Pain is among the most prevalent and distressing symptoms in advanced cancer, impairing physical, emotional, and social well-being. Management often requires support…

Date: 2026-07-06

Ratanasampil alleviates cognitive impairment in mice induced by chronic hypoxia by modulating inflammatory responses

Abstract: Chronic hypoxia at high altitudes contributes to cognitive decline, but effective therapies are lacking. The traditional Tibetan medicine Ratanasampil (RNSP) has…

Date: 2026-07-06