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Trends, survival and regional control of sentinel lymph node biopsy versus axillary dissection in cN0 breast cancer: a multicenter cohort in China

Abstract: Trials show that sentinel lymph node biopsy (SLNB) can replace completion axillary lymph node dissection (ALND) for selected cN0 patients without compromising survival…

Date: 2026-06-24

Outcomes of malignant orbital tumors: a 22-year Norwegian single-center series

Abstract: To evaluate outcome data for patients with malignant orbital tumors treated at Haukeland University Hospital over a 22 year period and compare them with existing…

Date: 2026-06-24

TRPV1-mediated calcium signaling underlies the synergistic pro-apoptotic effects of lidocaine and melatonin in SH-SY5Y neuroblastoma cells

Abstract: Lidocaine, an amide-type local anesthetic, and melatonin, a multifunctional indoleamine with mitochondrial regulatory and anticancer properties, have each been reported…

Date: 2026-06-24

NRS2002-stratified body composition and laboratory characteristics in hospitalized cancer patients assessed by bioelectrical impedance analysis

Abstract: The body composition and laboratory characteristics underlying Nutritional Risk Screening 2002 (NRS2002)-defined nutritional risk in hospitalized patients with cancer…

Date: 2026-06-24

Joint effects of severe obesity and inflammation on mortality in critically ill non?ST?segment elevation myocardial infarction patients: a cohort study with external validation

Abstract: To investigate the association between body mass index (BMI) and both in-hospital and 10-year all-cause mortality in critically ill non?ST?segment elevation myocardial…

Date: 2026-06-24

The predictive value of NT-proBNP/ALB ratio for in-hospital pericardial effusion in young acute myocardial infarction patients

Abstract: The incidence of acute myocardial infarction (AMI) in young adults (

Date: 2026-06-24

Intra-cardiac thrombus detection by electrocardiogram-gated cardiac computed tomography in hyperacute ischemic stroke

Abstract: Traditional workup with transthoracic echocardiogram (TTE) has limited yield in the diagnosis of suspected cardioembolic stroke. The current study aimed to determine the…

Date: 2026-06-24

Network meta-analysis of first-line R-CHOP-based regimens in MYC/BCL2 double-expressor diffuse large B-cell lymphoma

Abstract: Double-expressor lymphoma (DEL), characterized by concurrent overexpression of MYC and BCL2 without gene rearrangements, represents 20%–30% of DLBCL and confers inferior…

Date: 2026-06-23

Association of age at menopause with cardiovascular disease and mortality: insights from NHANES and a clinical cohort

Abstract: Age at menopause is closely associated with cardiovascular disease and mortality, whereas the underlying mechanisms remain unclear. This study employed mediation…

Date: 2026-06-23

Habit strength as a partial explanation of the association between self-efficacy and self-management behaviors in type 2 diabetes: a multicenter cross-sectional study

Abstract: While individual behavior is governed by both conscious control and unconscious automatic processes, the extent to which habit strength influences the relationship…

Date: 2026-06-23