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Total elbow arthroplasty for distal humeral fractures in the elderly population: good functional outcomes and a high implant survival rate can be expected after surgery

Abstract: Distal humeral fractures in elderly patients are difficult to treat due to poor bone quality and high complication rates. Total elbow arthroplasty (TEA) is an…

Date: 2026-06-17

Coencapsulation of doxorubicin and curcumin in liposomes modified with folic acid for reversal of drug resistance in glioma

Abstract: Multidrug resistance (MDR) critically limits doxorubicin (Dox) efficacy in glioma. To overcome this, we constructed a folic acid receptor (FAR)-targeted liposomal system…

Date: 2026-06-17

Comprehensive nursing intervention improves psychological outcomes, sleep quality, pain, and coping in patients with comorbid depression and thoracolumbar compression fracture

Abstract: Thoracolumbar compression fractures frequently coexist with depression, creating a self-reinforcing cycle of pain and psychological distress. Conventional nursing care…

Date: 2026-06-17

From routine full-spine radiographs to decision-oriented Risser stratification: an interpretable deep-learning approach

Abstract: Accurate assessment of remaining growth is crucial for risk stratification and treatment planning in adolescent idiopathic scoliosis (AIS). Risser staging is widely used…

Date: 2026-06-17

Microbiota metabolite butyrate alleviates intestinal inflammation associated with enhanced autophagy-related signaling in DSS-induced colitis

Abstract: The incidence of inflammatory bowel disease (IBD) has been demonstrated to be increased over recent decades. Butyrate derived from the gut microbiota is known to be…

Date: 2026-06-17

Increased severity and relapse rate in adult anti-nuclear matrix protein 2 antibody positive myositis patients with distal limb weakness: a retrospective study in China

Abstract: This study aimed to examine the clinical features and prognosis of patients with distal limb weakness in anti-nuclear matrix protein 2 antibody (anti-NXP2) positive…

Date: 2026-06-17

The aMAP score improves discrimination of prognostic models in hepatocellular carcinoma after radiofrequency ablation

Abstract: The aMAP score has proven a reliable model for predicting the risk of hepatocellular carcinoma (HCC) development in patients with various types of hepatitis, but its…

Date: 2026-06-17

Admission hyperglycemia, estimated glomerular filtration rate and outcome of acute ischemic stroke after mechanical thrombectomy: a mediation analysis

Abstract: Multiple factors influence the efficacy of mechanical thrombectomy (MT) in patients with acute ischemic stroke. This study aimed to clarify the association between…

Date: 2026-06-17

Dysphagia in patients with severe stroke: influencing factors and coping strategies

Abstract: Dysphagia is a common and serious complication in patients with severe stroke. This study aimed to identify independent risk factors for dysphagia in this population,…

Date: 2026-06-17

Targeted replacement of human ?? TCR in mice enhances antigen-specific B cell immunity

Abstract: The humanized (Hu) gamma delta (??) T cell receptor (TCR) -T1 (?? HuTCR-T1) mouse model represents a novel and versatile platform for investigating human-like immune…

Date: 2026-06-17