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Integrating lipid-related composite indices and explainable machine learning for coronary heart disease risk assessment

Abstract: Composite indices integrating inflammation and lipid metabolism have emerged as promising markers for coronary heart disease (CHD), yet their comparative performance and…

Date: 2026-06-17

The association of remnant cholesterol inflammatory index with the risk of major adverse cardiovascular events in patients with angina undergoing percutaneous coronary intervention: a retrospective study

Abstract: The remnant cholesterol-inflammation index (RCII), which combines remnant cholesterol (RC) and high-sensitivity C-reactive protein (hs-CRP), reflects both metabolic and…

Date: 2026-06-17

Retrospective cohort study assessing cardiovascular risk reduction through intensive blood pressure management in high-risk patients

Abstract: Hypertension remains a major global risk factor for cardiovascular disease. While clinical trials suggest that lower systolic blood pressure (SBP) levels reduce…

Date: 2026-06-17

Murray law-based quantitative flow ratio versus invasive fractional flow reserve in the left anterior descending coronary artery: impact of hydrostatic pressure correction and clinical implications

Abstract: Invasive fractional flow reserve (FFR) is the gold standard for guiding coronary revascularization. Angiography-derived FFR techniques such as the quantitative flow…

Date: 2026-06-17

Association between CALLY index and all-cause mortality in patients with rheumatoid arthritis

Abstract: The CALLY index reflects immune, inflammatory, and nutritional status, but its prognostic role in rheumatoid arthritis (RA) remains uncertain. We investigated whether…

Date: 2026-06-16

Predicting CAR-T outcomes in R/R DLBCL: a multicenter real-world study of a 5-index model

Abstract: The clinical management of relapsed or refractory diffuse large B?cell lymphoma (R/R DLBCL) has been transformed by chimeric antigen receptor T?cell therapy (CAR?T), yet…

Date: 2026-06-16

Neonatal reference intervals for salivary steroids: focus on prematurity, stressful events and perinatal betamethasone

Abstract: Painlessly obtained samples can improve diagnostics and care in paediatric conditions with affected steroidogenesis. To establish neonatal reference intervals (RIs) and…

Date: 2026-06-16

Association between sarcopenic obesity and mild cognitive impairment in patients with type 2 diabetes mellitus

Abstract: Type 2 diabetes mellitus (T2DM) is a major risk factor for cognitive decline. Sarcopenic obesity (SO), a metabolically detrimental trait, is common in people with T2DM.…

Date: 2026-06-16

Triglyceride–glucose related index and its association with coronary heart disease risk in patients with metabolic dysfunction-associated steatotic liver disease: a retrospective analysis based on type 2 diabetes mellitus

Abstract: The triglyceride–glucose (TyG) related index, as an emerging indicator of insulin resistance, has been shown to be closely associated with the clinical status (incidence…

Date: 2026-06-16

Earlier detection of melanoma using in vivo reflectance confocal microscopy—a retrospective analysis

Abstract: The incidence of melanoma has increased in recent decades. Non-invasive imaging devices, such as in vivo reflectance confocal laser microscopy (RCM), aid in the earlier…

Date: 2026-06-16