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A three-parameter complete blood count triage tool for monocytosis to prioritize hematology evaluation: development in MIMIC-IV and external validation in two independent cohorts

Abstract: Monocytosis is a common complete blood count (CBC) abnormality, but in non-hematology settings it may be difficult to distinguish reactive causes from patterns…

Date: 2026-09-25

Allogeneic hematopoietic cell transplantation for therapy-related hematological malignancies in patients with multiple myeloma

Abstract: Improved survival in multiple myeloma (MM) patients after high-dose chemotherapy, autologous hematopoietic cell transplantation (auto-HCT), and novel agents has led to…

Date: 2026-09-25

Bone microarchitecture and strength in obese women with and without polycystic ovary syndrome (PCOS): a peripheral quantitative computed tomography (pQCT) study

Abstract: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, but its skeletal impact remains unclear due to confounding obesity. Areal bone mineral density (BMD)…

Date: 2026-09-25

Baseline BMI and weight change in dilated cardiomyopathy: associations with LVEF, BNP, and NYHA class

Abstract: Baseline body mass index (BMI) and longitudinal weight change capture different clinical dimensions. We examined their concurrent associations with 12-month changes in…

Date: 2026-09-25

Association of ultrasound-derived fat fraction with carotid intima-media thickness and carotid plaque in patients with type 2 diabetes: an exploratory cross-sectional study

Abstract: To investigate the associations of continuous ultrasound-derived fat fraction (UDFF) with carotid intima-media thickness (CIMT) and prevalent carotid plaque in patients…

Date: 2026-09-25

Clinical characteristics and genotype–phenotype correlation analysis in 279 patients with 5?-reductase type 2 deficiency

Abstract: 5?-Reductase type 2 deficiency (5?-RD2) is an autosomal recessive differences/disorders of sex development caused by SRD5A2 gene mutations, characterized by impaired…

Date: 2026-09-25

Quantitative assessment of active charcot neuro-osteoarthropathy in diabetes using 18 F-sodium fluoride PET/CT

Abstract: No single imaging modality currently provides quantitative assessment of disease activity in active charcot neuro-osteoarthropathy (CNO) of the foot, either at diagnosis…

Date: 2026-09-25

Topical Egg yolk Oil and post-Laser recovery in atrophic acne scars: a retrospective propensity score-matched study with machine learning and SHAP analysis

Abstract: Prolonged epidermal recovery frequently complicates fractional carbon dioxide (CO 2 ) laser therapy for atrophic acne scars. This study aims to evaluate the potential…

Date: 2026-09-25

The child opportunity index and developmental outcomes in early childhood

Abstract: Neighborhood-level opportunity plays a critical but underexplored role in shaping a child's early developmental outcomes. We hypothesized that higher neighborhood…

Date: 2026-09-25

Point-of-care lactate in pediatric sepsis: a single-center observational study

Abstract: Lactate is a key biomarker in the assessment of sepsis, reflecting tissue hypoperfusion and correlating with disease severity and outcomes. However, reliance on standard…

Date: 2026-09-25