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Interocular asymmetry and ocular biometric patterns in pediatric high myopia: implications for early risk stratification

Abstract: To describe the clinical and ocular biometric characteristics of high myopia in children and adolescents, analyze the relationship between age and axial length (AL) and…

Date: 2026-05-25

The effect of multi-disciplinary treatment on surgical outcomes and kinematic gait patterns in patients undergoing primary unilateral knee unicompartmental arthroplasty: a retrospective cohort study

Abstract: To investigate the impact of the multi-disciplinary treatment (MDT) approach on surgical outcomes and kinematic gait parameters in patients undergoing primary unilateral…

Date: 2026-05-25

Is being a night owl associated with higher migraine-related disability in patients with migraine?

Abstract: Emerging evidence suggests that circadian rhythms may influence migraine pathophysiology through interactions between sleep-wake regulation and pain modulation pathways.…

Date: 2026-05-25

Risk factors for disease generalization in acetylcholine receptor antibody-positive ocular myasthenia: a multicenter retrospective study

Abstract: This study aimed to identify factors associated with secondary generalization in patients with ocular-onset myasthenia gravis (OoMG) who were positive for…

Date: 2026-05-25

Re-evaluating the lying-down test: a step-saving and well-tolerated diagnostic adjunct for horizontal canal benign paroxysmal positional vertigo

Abstract: The supine roll test (SRT) is the established diagnostic standard for horizontal canal benign paroxysmal positional vertigo (HC-BPPV). However, its clinical application…

Date: 2026-05-25

Real-world efficacy of eculizumab in generalized myasthenia gravis patients with poor early response to efgartigimod: a prospective cohort study

Abstract: The management of generalized myasthenia gravis (gMG) poses a therapeutic challenge. Efgartigimod, a neonatal Fc receptor (FcRn) inhibitor, has significant efficacy in…

Date: 2026-05-25

Cutaneous adverse events with antibody-drug conjugates: a FAERS-based pharmacovigilance study

Abstract: Antibody-drug conjugates (ADCs) have revolutionized oncology by integrating the target specificity of monoclonal antibodies with the potency of cytotoxic payloads.…

Date: 2026-05-25

Progression-directed ablative radiotherapy improves event-free survival in oligoprogressive NSCLC

Abstract: To assess the efficacy of progression-directed radiation therapy (PDRT) in patients with oligoprogressive non-small cell lung cancer (NSCLC), with particular focus on…

Date: 2026-05-25

Mechanistic and functional characterization of NETs/IL-17 as a therapeutic target in EMT and brain metastasis of lung adenocarcinoma

Abstract: Lung adenocarcinoma (LUAD) was known to have a propensity for brain metastasis. Neutrophil extracellular traps (NETs) played a role in facilitating tumor metastasis.…

Date: 2026-05-25

Immunotherapy plus induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemotherapy with cisplatin vs induction chemotherapy followed by two cycles of concurrent chemotherapy with cisplatin in locoregionally advanced nasopharyngeal carcinoma

Abstract: To compare the efficacy and safety of immunotherapy combined with induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemoradiotherapy with…

Date: 2026-05-25