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Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in osteoarthritis by integrating bioinformatics and machine learning

Abstract: Exosomes as important carriers of intercellular communication have frequently appeared in recent studies related to osteoarthritis (OA), while the specific mechanism of…

Date: 2025-08-20

Application of a hybrid virtual-physical teaching model integrating mixed reality and 3D printing in clinical joint orthopedic education

Abstract: The diagnosis and treatment of arthropathic orthopaedic conditions are inherently linked to anatomical structures, necessitating strong spatial visualization abilities…

Date: 2025-08-20

Disparities in liver transplant waitlist characteristics and outcomes among Hispanic compared to non-Hispanic adults

Abstract: Social determinants of health (SDOH) and transplant center characteristics have been associated with access to liver transplantation (LT) for Hispanic individuals. The…

Date: 2025-08-20

Predictors of futile recanalization after endovascular therapy in anterior circulation stroke with large core infarction

Abstract: There is a lack of data to predict futile recanalization (FR) after endovascular treatment (EVT) in acute anterior circulation large vessel occlusion (ACLVO) with large…

Date: 2025-08-20

Ruxolitinib and decitabine plus a busulfan–cyclophosphamide conditioning regimen for relapse prophylaxis in patients with high-risk acute myeloid leukemia or myelodysplastic syndromes

Abstract: Relapse remains the leading cause of treatment failure in high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome-IB (MDS-IB) patients after allogeneic…

Date: 2025-08-18

Application of laboratory-result-oriented modular teaching model in the training of clinical hematology laboratory interns

Abstract: Current teaching models for clinical hematology laboratory interns often prioritize theoretical knowledge dissemination over the practical application of skills directly…

Date: 2025-08-18

Oxidative stress-related biomarkers in thyroid eye disease: evidence from bioinformatics analysis and experimental validation

Abstract: Oxidative stress is a key contributor to the pathogenesis of the autoimmune condition thyroid eye disease (TED). However, its precise molecular mechanisms and reliable…

Date: 2025-08-18

Campylobacter infection presenting as pseudo-appendicitis in children: identifying predictors for early diagnosis

Abstract: To characterize Campylobacter enteritis presenting as pseudo-appendicitis and identify distinguishing predicting factors. This retrospective multicentre study included…

Date: 2025-08-18

Sound waves of progress: advancing endoscopic ultrasound in pediatric gastroenterology

Abstract: A substantial body of research validates the application of endoscopic ultrasound in adults in the management of biliary and pancreatic conditions. There is limited data…

Date: 2025-08-18

Evaluation of whole blood CD64 for identifying infection in neonates receiving hospital care

Abstract: Infection remains one of the most common causes of death in neonates. However, early detection of neonatal infections to inform treatment decisions remains clinically…

Date: 2025-08-18