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HMGB2 drives tumor progression and shapes the immunosuppressive microenvironment in hepatocellular carcinoma: insights from multi-omics analysis

Abstract: Background: Hepatocellular carcinoma (HCC) poses a significant health burden globally, with high mortality rates despite various treatment options. Immunotherapy,…

Date: 2024-08-23

Individualized activity recommendation based on a physical fitness assessment increases short- and long-term regular physical activity in people with multiple sclerosis in a retrospective cohort study

Abstract: Background: Despite the evidence of beneficial effects of physical activity (PA), people with multiple sclerosis (pwMS) are less physically active than the general…

Date: 2024-08-23

Prospective nutrition-inflammation markers for predicting early stoma-related complications in patients with colorectal cancer undergoing enterostomy

Abstract: Background: Enterostomy is important for radical resection of colorectal cancer (CRC). Nevertheless, the notable occurrence of complications linked to enterostomy…

Date: 2024-08-23

Clinical parameters in patients with halitosis: a cross-sectional study

Abstract: Background: Halitosis, a socially and psychologically impactful condition often resulting from oral or systemic issues, is exacerbated by factors like aging, poor oral…

Date: 2024-08-23

Associations between SII, SIRI, and cardiovascular disease in obese individuals: a nationwide cross-sectional analysis

Abstract: Background: Systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) are comprehensive markers of inflammatory status. However, the…

Date: 2024-08-22

Unraveling the interplay: early-stage atrial functional mitral regurgitation and left atrial electrical substrate in atrial fibrillation patients

Abstract: Background: Atrial fibrillation (AF) triggers atrial remodeling, impacting atrial function and ablation efficacy. This remodeling leads to atrial cardiomyopathy and…

Date: 2024-08-22

T-cell exhaustion-related genes in Graves’ disease: a comprehensive genome mapping analysis

Abstract: Background: T-cell exhaustion (Tex) can be beneficial in autoimmune diseases, but its role in Graves’ disease (GD), an autoimmune disorder of the thyroid, remains…

Date: 2024-08-22