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Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation

Abstract: Understanding how midlife risk factors influence age at onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife adiposity…

Date: 2023-08-10

Construction and Effect of the Three-Level and Two-Stage Screening Mode for Age-Related Hearing Loss: A Study Based on the Community in Shanghai, China

Abstract: Age-related hearing loss is known as presbycusis, whose definition is hearing loss caused by aging and degeneration of auditory organs in the older adults. The…

Date: 2023-08-10

Emerging Trends and Focus in Human Skin Microbiome Over the Last Decade: A Bibliometric Analysis and Literature Review

Abstract: The skin is the largest heterogeneous organ in the human body, responsible for water homeostasis and surface thermoregulation. It also acts as the first host barrier…

Date: 2023-08-10

Understanding people’s decisions when choosing or declining a kidney transplant: a qualitative evidence synthesis

Abstract: Objectives To synthesise qualitative research exploring patients’ perspectives, experiences and factors influencing their decision-making preferences when choosing or…

Date: 2023-08-10

The STAIR OF KNOWLEDGE—a codesigned intervention to prevent pressure ulcers, malnutrition, poor oral health and falls among older persons in nursing homes in Sweden: development of a complex intervention

Abstract: Objectives To describe the development of a codesigned complex intervention intended to prevent the risks of pressure ulcers, malnutrition, poor oral health and falls…

Date: 2023-08-10

Antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease: protocol for a systematic review and network meta-analysis of randomised controlled trials

Abstract: Introduction The optimal antithrombotic regimen to reduce the risk of vascular events in patients with peripheral arterial disease (PAD) is contentious. This systematic…

Date: 2023-08-10

Dual bronchodilators in Bronchiectasis study (DIBS): protocol for a pragmatic, multicentre, placebo-controlled, three-arm, double-blinded, randomised controlled trial studying bronchodilators in preventing exacerbations of bronchiectasis

Abstract: Introduction Bronchiectasis is a long-term lung condition, with dilated bronchi, chronic inflammation, chronic infection and acute exacerbations. Recurrent exacerbations…

Date: 2023-08-10