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Serum interleukin-40 increases in anti-AchR antibody-positive myasthenia gravis and correlates with disease activity

Abstract: Interleukin-40 (IL-40), as an immune regulatory factor discovered in recent years, mainly plays a role in B-cell-related immune responses and is involved in the…

Date: 2025-09-17

B-cells and non-B-cells immunoglobulins expression in canine perianal gland tumours: a preliminary study

Abstract: Although the focus in tumor immunology has been on T cells, B cells may play a crucial role in modulating tumor responses. Among products released in the tumour…

Date: 2025-09-17

Identification of HLA-A , HLA-B , and HLA-C triple homozygous and double homozygous donors: a path toward synthetic superdonor advanced therapeutic medicinal products

Abstract: Human-induced pluripotent stem cells with broad immune compatibility are highly desirable for regenerative medicine applications. Human leukocyte antigen (HLA) class I…

Date: 2025-09-16

Association between peripheral thyroid sensitivity defined by the FT3/FT4 ratio and composite adverse outcome among inpatients with heart failure

Abstract: The free triiodothyronine to free thyroxine (FT3/FT4) ratio is an indicator of peripheral thyroid hormone sensitivity. However, its prognostic value in heart failure…

Date: 2025-09-16

Lesion size and cystic morphology are key determinants of parathyroid hormone washout in primary hyperparathyroidism

Abstract: Accurate preoperative localization of parathyroid adenomas is of great importance to ensure targeted and effective surgical treatment of primary hyperparathyroidism…

Date: 2025-09-16

Predictive factors for HbA1c and weight loss associated with semaglutide treatment in type 2 diabetes mellitus: real-world clinical evidence

Abstract: This study aimed to identify clinical predictors associated with reductions in HbA1c and weight among patients with type 2 diabetes mellitus (T2DM) treated with…

Date: 2025-09-16

Relationships among the triglyceride-glucose index, its changes, and the development of metabolically obese normal weight are strengthened by increased visceral fat area

Abstract: Metabolically obese normal weight (MONW), obesity with a normal body mass index, is often neglected due to the seemingly normal weight but has a high risk of metabolic…

Date: 2025-09-16

Th17-associated cytokine gene hypomethylation reflects epigenetic dysregulation in graves’ disease

Abstract: Graves’ disease (GD) is an organ-specific autoimmune disorder characterized by the presence of thyroid-stimulating hormone receptor autoantibodies (TRAb), leading to…

Date: 2025-09-16

Current status of national regulations on tanning bed use and workers' protection from solar ultraviolet radiation: results from a global International League of Dermatological Societies (ILDS) questionnaire study

Abstract: Exposure to ultraviolet radiation (UVR) is the most important risk factor for the development of skin cancer. Outdoor workers and people who use tanning beds belong to…

Date: 2025-09-16

Safety and efficacy of ultrasound-guided distal forearm median nerve block for pediatric trigger thumb release: a retrospective observational study in a southern Chinese cohort

Abstract: The aim of this study was to evaluate the clinical outcomes of ultrasound-guided distal forearm median nerve block (UDFMNB) in children undergoing A1 pulley release. We…

Date: 2025-09-16