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Acanthosis nigricans and acrochordons as clinical markers of metabolic disturbance during pregnancy: a prospective cohort study

Abstract: This study investigated the prevalence of acanthosis nigricans and acrochordons as potential markers of diabetes or insulin resistance in diabetic and non-diabetic…

Date: 2025-09-12

Lipocalin-2 in preoperative cerebrospinal fluid is a biomarker for postoperative delirium after hip fracture surgery in older adults: a prospective cohort study

Abstract: Postoperative delirium (POD) is a common central nervous system complication in older adult surgical patients. At present, the mechanism for POD is still unclear.…

Date: 2025-09-12

Medication adherence in obsessive-compulsive disorders and evaluation of effective adherence support strategies

Abstract: Medication adherence is a critical component in the treatment of psychiatric conditions such as obsessive-compulsive disorder (OCD). Poor adherence is associated with an…

Date: 2025-09-12

Associations between intelligence, affective temperament, and parental bonding with educational level

Abstract: Educational level is an important aspect of one's life and is associated with biopsychosocial and economic factors. The present study aimed to investigate the…

Date: 2025-09-12

MRI-based SIR quantitative biomarkers: a novel imaging diagnostic strategy for thyroid eye disease activity staging

Abstract: To evaluate the diagnostic efficacy of magnetic resonance imaging (MRI)-based signal intensity ratio (SIR) between extraocular muscles and white matter/temporal muscle…

Date: 2025-09-12

Real-world efficacy of MiniMed™780G recommended settings (glycemic target 100 mg/dL, active insulin time 2 hours) in youth and young adults with type 1 diabetes

Abstract: Despite growing evidence supporting the efficacy and safety of the MiniMed™ 780G recommended settings (Glucose Target 100 mg/dL and Active Insulin Time 2 hours), their…

Date: 2025-09-12

Retinal vascular alterations as assessment indicators of atherosclerotic cardiovascular disease risk in dyslipidemia patients

Abstract: Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global mortality, particularly among individuals with dyslipidemia. Traditionally, the retina…

Date: 2025-09-12

Early assessment and analysis of high-risk factors of neurodevelopmental impairment in neonates with congenital diaphragmatic hernia

Abstract: This study aimed to retrospectively analyze clinical data of neonates with congenital diaphragmatic hernia (CDH) to investigate risk factors for neurodevelopmental…

Date: 2025-09-12

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

Abstract: Artificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed…

Date: 2025-09-12

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Abstract: Colorectal laterally spreading tumors (LSTs) are defined as non-protruding neoplasms exceeding 10 mm in diameter that grow primarily along the intestinal wall. The…

Date: 2025-09-12