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Efficacy and safety of carbon dioxide insufflation for brain protection for patients undergoing planned left-sided open heart valve surgery: protocol for a multicentre, placebo-controlled, blinded, randomised controlled trial (the CO2 Study)

Abstract: Introduction Brain injury is common following open heart valve surgery. Carbon dioxide insufflation (CDI) has been proposed to reduce the incidence of brain injury by…

Date: 2023-05-17

Care coordination across healthcare systems: development of a research agenda, implications for practice, and recommendations for policy based on a modified Delphi panel

Abstract: Objective For large, integrated healthcare delivery systems, coordinating patient care across delivery systems with providers external to the system presents challenges.…

Date: 2023-05-17

Urban neighbourhood elements that influence psychoactive substance use among populations with adverse childhood experiences: a scoping review protocol

Abstract: Introduction Adverse childhood experiences (ACEs) are stressful or traumatic events experienced before the age of 18 years old. ACEs have been associated with an…

Date: 2023-05-17

Staffing levels and hospital mortality in England: a national panel study using routinely collected data

Abstract: Objectives Examine the association between multiple clinical staff levels and case-mix adjusted patient mortality in English hospitals. Most studies investigating the…

Date: 2023-05-17

Efficacy of focal high-dose-rate brachytherapy in the treatment of patients diagnosed with low or favourable intermediate-risk prostate cancer—a protocol for a randomised controlled trial

Abstract: Introduction Prostate cancer (PCa) is men’s second most predominant cancer worldwide. Because the prostate-specific antigen test is used in diagnostics, PCa is more…

Date: 2023-05-17

ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK

Abstract: Purpose Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral…

Date: 2023-05-17

A Novel Informatics Tool to Detect Periprocedural Antibiotic Allergy Adverse Events for Near Real-time Surveillance to Support Audit and Feedback

Abstract: Importance Standardized processes for identifying when allergic-type reactions occur and linking reactions to drug exposures are limited. Objective To develop an…

Date: 2023-05-17

The importance of chest CT severity score and lung CT patterns in risk assessment in COVID-19-associated pneumonia: a comparative study

Abstract: Introduction: Chest computed tomography (CT) is suitable to assess morphological changes in the lungs. Chest CT scoring systems (CCTS) have been developed and use in…

Date: 2023-05-17

Oral Health in migrants children in Melilla, Spain

Abstract: Numerous developing countries’ socioeconomic and political issues resulted in a significant migratory phenomenon, which poses a health burden for the nations that…

Date: 2023-05-16

Home-Based Exercise Training in the Recovery of Multisystem Inflammatory Syndrome in Children: A Case Series Study

Abstract: Objective: To assess the potential therapeutic role of exercise on health-related quality of life, assessed by the Pediatric Outcomes Data Collection Instrument (PODCI),…

Date: 2023-05-16