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Phenotypes of synovial fluid Treg cells in checkpoint blockade-related inflammatory arthritis

Abstract: Regulatory T (Treg) cells may become dysregulated in checkpoint blockade-related inflammatory arthritis (CBIA), and we aimed to profile phenotypes and cytokine-secreting…

Date: 2025-09-10

Circulatory cathepsin K as biomarkers in older adults with sarcopenia: a case-control study

Abstract: This study explores the relationship between circulating cathepsin K (CatK) and cathepsin D (CatD) levels and sarcopenia in older adults. This case-control study…

Date: 2025-09-10

A real-world study of polyenyl phosphatidylcholine in the management of patients with metabolic dysfunction-associated fatty liver disease in China clinical practice

Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) is highly prevalent in China. Clinical evidence supporting the role of polyenyl phosphatidylcholine (PPC) in…

Date: 2025-09-10

GLP-1 receptor agonist increase retained gastric contents on EGD and same-day colonoscopy reduces this risk

Abstract: With the rise in glucagon-like peptide 1 receptor agonist (GLP-1RA) medication usage for Type 2 diabetes mellitus and weight loss, concerns have been raised regarding…

Date: 2025-09-10

Surgery versus neoadjuvant chemoradiotherapy followed by surgery in locally advanced gastrointestinal tract cancers

Abstract: Gastrointestinal tract cancer is still prevalent in the world. Localized GI cancer treatment has greatly relied on surgery, even for locally advanced diseases. The goal…

Date: 2025-09-10

Spinocerebellar ataxias masquerading as movement disorders: clinical and genetic characterization

Abstract: Spinocerebellar ataxias (SCAs) exhibit substantial clinical and genetic heterogeneity. SCAs primarily present with progressive ataxia as the cardinal clinical feature.…

Date: 2025-09-10

Elevated remnant cholesterol impairs sleep characteristics in individuals with newly diagnosed moderate-to-severe obstructive sleep apnea: a cross-sectional case–control study

Abstract: Although obstructive sleep apnea (OSA) is widely recognized as a common contributor to disruptions in sleep and lipid metabolism, there is still a lack of concrete…

Date: 2025-09-10

Efficacy and safety of successful mechanical thrombectomy in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke

Abstract: To explore the efficacy and safety of successful mechanical thrombectomy (MT) in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke…

Date: 2025-09-10

Communication practices and information exchange for caregivers of children with cancer in Pakistan

Abstract: Information exchange is a core component of communication that has been understudied globally. This study sought to examine eight core functions of communication,…

Date: 2025-09-09

Soluble B-cell maturation antigen as a serum marker of MRD in patients with multiple myeloma

Abstract: Serum soluble B-cell maturation antigen (sBCMA) has been shown to correspond to high disease burden in uncontrolled Multiple Myeloma (MM). However, it has not been…

Date: 2025-09-09