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Impact of per- and polyfluoroalkyl substances on diabetic kidney disease

Abstract: This study aims to elucidate the mechanistic role of Per- and Polyfluoroalkyl Substances (PFAS) in the pathogenesis and progression of diabetic kidney disease (DKD).…

Date: 2025-09-09

Cross-lagged analysis of burnout and insomnia in older adult patients with diabetes mellitus complicated by hypertension: a 1-year longitudinal follow-up study

Abstract: The aim of this study is to investigate the longitudinal bidirectional relationship between disease management burnout and insomnia symptoms in older adult patients with…

Date: 2025-09-09

Prolactin secreting pituitary neuroendocrine tumors treated by dopamine agonists: predictors of response

Abstract: To date, no specific criteria have been clearly established to predict the response to dopamine agonists (DA), and a universally accepted definition of DA resistance…

Date: 2025-09-09

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

Abstract: Heredity and epigenetic factors contribute to the pathogenesis of neutrophil-cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Cytotoxic T lymphocyte-associated…

Date: 2025-09-09

The relationship between novel inflammatory markers SII, SIRI, MHR, UHR and insulin resistance in patients with type 2 diabetes: based on a retrospective analysis

Abstract: This study aims to investigate the relationship between newly identified inflammatory indicators and IR in patients with T2DM, thereby providing a reference basis for…

Date: 2025-09-09

Characteristics of clinical manifestations and molecular genetics of inherited hyperhomocysteinemia in children and adolescents: a single center experience from China

Abstract: Accurate identification of the genetic cause of inherited hyperhomocysteinemia (HHcy) is essential for targeted therapies and individualized treatment. However, reported…

Date: 2025-09-09

Benign acute childhood myositis: a retrospective cohort study from a large tertiary care children's hospital

Abstract: Benign acute childhood myositis (BACM) is a common self-limiting condition. While studies in other regions have described the epidemiology and outcomes of BACM, there is…

Date: 2025-09-09

Development and internal validation of a mammography-based model fusing clinical, radiomics, and deep learning models for sentinel lymph node metastasis prediction in breast cancer

Abstract: To develop a mammography (MG)-based post-fusion model combined with Clinical, Radiomics, and Deep Learning Models to evaluate the status of sentinel lymph node (SLN) in…

Date: 2025-09-09

Development and validation of a nomogram for pressure injury risk prediction in stroke patients: a retrospective cohort study

Abstract: Retrospective cohort study. This study aimed to identify independent risk factors for pressure injury (PI) during the post-stroke recovery phase, develop and validate a…

Date: 2025-09-09

Ease pediatric emergency department crowding in Switzerland with high-quality telephone triage: a prospective multicenter study

Abstract: This is the first study evaluating the picture of a pediatric telephone triage service's (PTTS) quality from the hospital, telemedical, and patient perspective, to…

Date: 2025-09-09