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Comparative Safety and Changes in Immunologic and Virologic Parameters of Dolutegravir versus Efavirenz-Based Antiretroviral Therapies Among HIV Patients: A Retrospective Cohort Study

Abstract: Acquired immune deficiency syndrome (AIDS) is a human infectious disease with no cure. It is a stage of infection where advanced immunosuppression, progressive clinical…

Date: 2023-04-27

AS- Blunts Osteoporosis by Inhibition of Bone Resorption

Abstract: Bone growth is a dynamic process and involves continuous remodeling. It primarily depends on the homeostasis between the resorption of osteoclasts and the formation of…

Date: 2023-04-27

Psychological recovery and well-being of spouses of patients with prostate cancer 5 years after primary treatment in Finland: a follow-up survey

Abstract: Objective and setting To study longitudinally cancer-related experiences of spouses of patients with prostate cancer and the predictors of their psychological recovery…

Date: 2023-04-27

Parental experiences of childcare in an informal urban settlement: qualitative interview findings from the Nairobi Early Childcare in Slums (NECS) project

Abstract: Objectives To gain an in-depth understanding of parent/carers’ perspectives on, and decision-making about, early childhood care in general, and paid childcare…

Date: 2023-04-27

Influence of health system and patient characteristics on expectations and outcome in total hip arthroplasty patients in the Dutch-German border region: protocol for a mixed-methods prospective observational comparative study (hip across)

Abstract: Introduction Total hip arthroplasty (THA) is the treatment of choice for end-stage osteoarthritis of the hip. Management of THA differs between countries, and it is…

Date: 2023-04-27

Protocol for a realist and social return on investment evaluation of the use of patient-reported outcomes in four value-based healthcare programmes

Abstract: Introduction There is growing recognition that in order to remain sustainable, the UK’s National Health Service must deliver the best patient outcomes within available…

Date: 2023-04-27

Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdrawal of life-sustaining measures

Abstract: Introduction In donation after circulatory determination of death, death is declared 5 min after circulatory arrest. This practice assumes, but does not explicitly…

Date: 2023-04-27

Mental health of new and recent graduates during the university-to-work transition: a scoping review protocol

Abstract: Introduction University students face challenges when starting their careers and entering the workforce after tertiary education is associated with negative…

Date: 2023-04-27

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial

Abstract: Introduction COVID-19 convalescent plasma (CCP) is a possible treatment option for COVID-19. A comprehensive number of clinical trials on CCP efficacy have already been…

Date: 2023-04-27

Diabetes care cascade and associated factors in 10 700 middle-aged adults in four sub-Saharan African countries: a cross-sectional study

Abstract: Objectives We investigated progression through the care cascade and associated factors for people with diabetes in sub-Saharan Africa to identify attrition stages that…

Date: 2023-04-27