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Perioperative management of severe factor VII deficiency: a single-center experience in China

Abstract: Inherited factor VII (FVII) deficiency is a rare autosomal recessive disorder whose clinical phenotypes are highly variable. Many studies have observed the absence of a…

Date: 2025-09-22

Substance use risk screening and associated factors among Costa Rican secondary students: a nationally representative analysis

Abstract: Adolescent substance use (SU) is a significant public health concern in Latin America, however, representative data to guide prevention efforts remain limited. This…

Date: 2025-09-22

The association between gestational hypothyroidism in pregnant women with preeclampsia, maternal liver function indicators, and neonatal birth weight: a study in Chinese pregnant women

Abstract: Birth weight serves as a critical indicator of neonatal survival. Preeclampsia represents a serious complication during pregnancy and is closely associated with…

Date: 2025-09-22

Functional near-infrared spectroscopy as a diagnostic aid for stable schizophrenia

Abstract: Cognitive impairment in schizophrenia (SCZ) is common, but the mechanism remains unclear. This study aimed to investigate whether brain activation during the functional…

Date: 2025-09-22

Associations between Cloninger’s temperament and character traits and light preference

Abstract: It is unknown whether light preference (brightness or darkness) is associated with Cloninger’s temperament and character traits. This study examined the association…

Date: 2025-09-22

Analysis of refractive development characteristics in school-age children based on biometric measurements: a cross-sectional study involving 12,025 primary school students from Xingtai City

Abstract: To investigate refractive development, myopia prevalence trends, and correction status among 6–12-year-old primary students in Xingtai, Hebei, China, and provide…

Date: 2025-09-22

Comparative performance of large language models for patient-initiated ophthalmology consultations

Abstract: Large language models (LLMs) are increasingly accessed by lay users for medical advice. This study aims to conduct a comprehensive evaluation of the responses generated…

Date: 2025-09-22

Cyclobenzaprine-related adverse events: a comprehensive pharmacovigilance analysis using the FDA Adverse Event Reporting System

Abstract: Cyclobenzaprine, a centrally-acting muscle relaxant, is widely used for the treatment of musculoskeletal pain. Despite its efficacy, concerns regarding its safety…

Date: 2025-09-22

The relationship between number of pregnancies and serum 25-hydroxyvitamin D levels in women with a prior pregnancy: a cross - sectional analysis, machine learning - based prediction model, and SHAP - assisted feature importance evaluation

Abstract: The primary aim of this study is to explore the association between gravidity and serum 25-hydroxyvitamin D [25(OH)D] levels in women, as existing research rarely…

Date: 2025-09-22

Efficacy and safety of immune checkpoint inhibitor rechallenge therapy in the treatment of advanced acquired immune-resistant non-small cell lung cancer: a retrospective study

Abstract: Patients with advanced non-small cell lung cancer who have failed first-line immunotherapy and lack driver gene mutations face limited options for subsequent treatment.…

Date: 2025-09-22