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Identification and visualization of fusion gene subtypes in APL using spatial attention mechanisms in vision models

Abstract: Acute promyelocytic leukemia (APL) features leukemic cell differentiation arrest at the promyelocytic stage, mainly due to the t (15;17), (q24; q21) translocation that…

Date: 2025-07-30

Mechanism of action of decitabine in treating acute lymphoblastic leukemia

Abstract: This study aimed to evaluate the underlying mechanisms of decitabine (DAC) in inhibiting acute T-acute lymphoblastic leukemia (T-ALL) cell proliferation and promoting…

Date: 2025-07-30

Venous thromboembolism prophylaxis practices in hematology/oncology patients admitted to neurological intensive care units

Abstract: Venous thromboembolism (VTE) presents a significant challenge for neurocritically ill patients with cancer due to the combined risks of thrombosis and bleeding. This…

Date: 2025-07-30

Can the MMP-9/NGAL ratio be a diagnostic biomarker for the diagnosis of endometrioma in infertile patients?

Abstract: In this study, we aimed to investigate whether serum NGAL, MMP-9 and the MMP-9/NGAL ratio, which are inflammatory markers used for the diagnosis and follow-up of some…

Date: 2025-07-30

Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

Abstract: Cutaneous melanoma (CM) is a highly malignant tumor originating from melanocytes. Rising incidence rates pose a significant burden on global health and economy. Advanced…

Date: 2025-07-30

Implementation of a spaced-repetition approach to enhance undergraduate learning and engagement in paediatrics

Abstract: Knowledge retention is crucial in medical education, yet traditional study methods often fail to ensure long-term recall. Spaced repetition, a cognitive learning…

Date: 2025-07-30

Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China

Abstract: Medulloblastoma (MB) is the most common malignant pediatric brain tumor, yet systematic studies on molecular characteristics and treatment efficacy in Chinese pediatric…

Date: 2025-07-30

Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study

Abstract: Levosimendan is used off-label in pediatrics and pharmacokinetic (PK) data in this population are scarce. The only study in critically ill patients on extracorporeal…

Date: 2025-07-30

Study on the 1990–2021 trend of global childhood respiratory infection and tuberculosis disease burden and related risk factors

Abstract: Respiratory tract infections (RTIs) and tuberculosis (TB) impose a critical global health burden on children, serving as leading causes of morbidity and mortality. Lower…

Date: 2025-07-30

High prevalence but low referral rate of adrenal incidentalomas in a Lebanese tertiary hospital

Abstract: Adrenal incidentalomas (AI) are being more frequently reported with the advent of medical imaging. Studies on their prevalence, characteristics and functional status are…

Date: 2025-07-29