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Acupuncture attenuates experimental autoimmune thyroiditis by modulating intestinal microbiota and palmitic acid metabolism

Abstract: Introduction: Autoimmune thyroiditis (AIT) is a common and chronic autoimmune disease. Recent evidence indicates that serum metabolites and dysbiosis of the intestinal…

Date: 2025-04-28

Associations between insulin resistance and low back pain risk in US adults: a cross-sectional study

Abstract: Background: Insulin resistance is one of the major pathophysiological features of type 2 diabetes mellitus. Studies have revealed the association between type 2 diabetes…

Date: 2025-04-28

Novel integrative models to predict the severity of inflammation and fibrosis in patients with drug-induced liver injury

Abstract: Background and aims: Drug-induced liver injury (DILI) is becoming a worldwide emerging problem. However, few studies focus on the diagnostic performance of non-invasive…

Date: 2025-04-28

Integral kidney function assessment in pediatric patients with glycogen storage diseases

Abstract: Introduction: Glycogen storage diseases (GSDs) are a group of hereditary metabolic disorders with variable clinical manifestations, depending on the enzyme and organ…

Date: 2025-04-28

Immunotherapy for neuromyelitis optica spectrum disorder: a comparative analysis of efficacy and safety of azathioprine, mycophenolate mofetil, tacrolimus, and rituximab

Abstract: Background and purpose: Biologic therapies are anticipated to dominate the treatment landscape for neuromyelitis optica spectrum disorders (NMOSD) in the future. Despite…

Date: 2025-04-28

Resolution of anti-GAD-associated autoimmune encephalitis in patients treated with efgartigimod

Abstract: Introduction: Temporal lobe epilepsy (TLE) is a significant clinical phenotype of anti-glutamic acid decarboxylase (GAD)-associated disease, which is characterized by…

Date: 2025-04-28

Repeatability, reliability, and stability of eye movement measurements in Parkinson’s disease, cerebellar ataxia, and healthy adults

Abstract: Introduction: Eye movements have been proposed as biomarkers to track disease progression and treatment effects in neurological diseases. Before such variables are used…

Date: 2025-04-28

Single-cell transcriptomics and functional validation revealed PLEKHA5-L as a promoter of growth and migration in brain metastatic melanoma cells

Abstract: Background: Melanoma brain metastasis is an lethal event. Investigating the molecules that potentially promoted melanoma metastasis is important for targeted therapy.

Date: 2025-04-28

Sexual dysfunction and quality of life in cervical and endometrial cancer patients before and after low-dose-rate brachytherapy: a cohort study

Abstract: Background: Research on low-dose-rate (LDR) brachytherapy for gynecological cancer primarily examines treatment toxicity while overlooking aspects such as sexual desire,…

Date: 2025-04-28