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Real-world efficacy of MiniMed™780G recommended settings (glycemic target 100 mg/dL, active insulin time 2 hours) in youth and young adults with type 1 diabetes

Abstract: Despite growing evidence supporting the efficacy and safety of the MiniMed™ 780G recommended settings (Glucose Target 100 mg/dL and Active Insulin Time 2 hours), their…

Date: 2025-09-12

Retinal vascular alterations as assessment indicators of atherosclerotic cardiovascular disease risk in dyslipidemia patients

Abstract: Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global mortality, particularly among individuals with dyslipidemia. Traditionally, the retina…

Date: 2025-09-12

Early assessment and analysis of high-risk factors of neurodevelopmental impairment in neonates with congenital diaphragmatic hernia

Abstract: This study aimed to retrospectively analyze clinical data of neonates with congenital diaphragmatic hernia (CDH) to investigate risk factors for neurodevelopmental…

Date: 2025-09-12

Mapping artificial intelligence adoption in hepatology practice and research: challenges and opportunities in MENA region

Abstract: Artificial intelligence (AI) is increasingly relevant to hepatology, yet real-world adoption in the Middle East and North Africa (MENA) is uncertain. We assessed…

Date: 2025-09-12

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Abstract: Colorectal laterally spreading tumors (LSTs) are defined as non-protruding neoplasms exceeding 10 mm in diameter that grow primarily along the intestinal wall. The…

Date: 2025-09-12

Navigating the diagnostic challenges of myoclonus in neurodegenerative disorders: video-EEG/polygraphy, clinical vignettes, and narrative analysis

Abstract: Myoclonus—sudden, brief, involuntary muscle jerks—is a frequent and diagnostically challenging feature across neurodegenerative disorders. Unlike epileptic myoclonus,…

Date: 2025-09-12

Tracking prodromal Parkinson’s disease: a five-year follow-up of the PARCAS cohort

Abstract: The updated International Parkinson and Movement Disorders Society (MDS) research criteria for prodromal Parkinson’s disease (pPD) enable pPD probability assessment. In…

Date: 2025-09-12

Transradial approach in vertebral artery stenting

Abstract: The transradial approach (TRA) has been gaining attraction for endovascular procedures. This study aimed to compare the efficacy and safety of the TRA vs. the…

Date: 2025-09-12

Longitudinal evaluation of T-cell responses to Pfizer-BioNTech and Janssen SARS-CoV-2 vaccines as boosters in Ghanaian adults

Abstract: In Ghana, at least five different COVID-19 vaccines based on mRNA or adenovirus vector delivery platforms have been authorized by the Ghana Health Service for…

Date: 2025-09-12

The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways

Abstract: Immunosuppressive factors within the tumor microenvironment hinder effective antitumor immune responses and limit the efficacy of current immunotherapies.…

Date: 2025-09-12