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Spinocerebellar ataxias masquerading as movement disorders: clinical and genetic characterization

Abstract: Spinocerebellar ataxias (SCAs) exhibit substantial clinical and genetic heterogeneity. SCAs primarily present with progressive ataxia as the cardinal clinical feature.…

Date: 2025-09-10

Elevated remnant cholesterol impairs sleep characteristics in individuals with newly diagnosed moderate-to-severe obstructive sleep apnea: a cross-sectional case–control study

Abstract: Although obstructive sleep apnea (OSA) is widely recognized as a common contributor to disruptions in sleep and lipid metabolism, there is still a lack of concrete…

Date: 2025-09-10

Efficacy and safety of successful mechanical thrombectomy in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke

Abstract: To explore the efficacy and safety of successful mechanical thrombectomy (MT) in elderly patients with anterior circulation large vessel occlusion acute ischemic stroke…

Date: 2025-09-10

Communication practices and information exchange for caregivers of children with cancer in Pakistan

Abstract: Information exchange is a core component of communication that has been understudied globally. This study sought to examine eight core functions of communication,…

Date: 2025-09-09

Soluble B-cell maturation antigen as a serum marker of MRD in patients with multiple myeloma

Abstract: Serum soluble B-cell maturation antigen (sBCMA) has been shown to correspond to high disease burden in uncontrolled Multiple Myeloma (MM). However, it has not been…

Date: 2025-09-09

Impact of per- and polyfluoroalkyl substances on diabetic kidney disease

Abstract: This study aims to elucidate the mechanistic role of Per- and Polyfluoroalkyl Substances (PFAS) in the pathogenesis and progression of diabetic kidney disease (DKD).…

Date: 2025-09-09

Cross-lagged analysis of burnout and insomnia in older adult patients with diabetes mellitus complicated by hypertension: a 1-year longitudinal follow-up study

Abstract: The aim of this study is to investigate the longitudinal bidirectional relationship between disease management burnout and insomnia symptoms in older adult patients with…

Date: 2025-09-09

Prolactin secreting pituitary neuroendocrine tumors treated by dopamine agonists: predictors of response

Abstract: To date, no specific criteria have been clearly established to predict the response to dopamine agonists (DA), and a universally accepted definition of DA resistance…

Date: 2025-09-09

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

Abstract: Heredity and epigenetic factors contribute to the pathogenesis of neutrophil-cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Cytotoxic T lymphocyte-associated…

Date: 2025-09-09

The relationship between novel inflammatory markers SII, SIRI, MHR, UHR and insulin resistance in patients with type 2 diabetes: based on a retrospective analysis

Abstract: This study aims to investigate the relationship between newly identified inflammatory indicators and IR in patients with T2DM, thereby providing a reference basis for…

Date: 2025-09-09