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Deep phenotyping of eyes shut homolog-associated retinopathy based on visual impairment patterns

Abstract: This study aimed to classify the phenotypes of eyes shut homolog ( EYS )-associated retinopathy based on visual impairment patterns and investigate their…

Date: 2025-09-08

Global burden and projections of stroke and its subtypes attributable to high alcohol use during 1990–2021: insights from the global burden of disease study 2021

Abstract: Stroke represents a critical public health challenge with far-reaching global implications for human health. In this study, we seek to characterize the global trends in…

Date: 2025-09-08

An ingenious 3D-printed navigating template for accurate screw placement in lumbar spinal stenosis

Abstract: To investigate the feasibility, accuracy, and safety of using a 3D-printed navigating template in transforaminal lumbar intervertebral fusion (TLIF) for treating lumbar…

Date: 2025-09-08

The burden of motor neuron diseases in Asia, 1990–2021: temporal patterns and age-period-cohort analyses

Abstract: This study aims to characterize the temporal trends of motor neuron diseases (MNDs) burden in Asia from 1990 to 2021, estimate their age, period and cohort effects, and…

Date: 2025-09-08

Diabetic Striate Syndrome: an uncommon complication of diabetes requiring further conceptual expansion

Abstract: Diabetic Striate Syndrome (DSS) is a rare complication of diabetes, clinically characterized by chorea-like involuntary movements and contralateral basal ganglia…

Date: 2025-09-08

Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85?years

Abstract: Previous studies have demonstrated sex differences in the association between body mass index (BMI) and hemorrhagic stroke. Cerebral microbleed (CMB) is a clinically…

Date: 2025-09-08

Polyfunctionality of CD4 + T lymphocytes in buffaloes and cattle: comparative antigen-specific cytokine responses in bovine tuberculosis infection

Abstract: Bovine tuberculosis (BTB), caused by Mycobacterium bovis , is a chronic infectious disease of major veterinary and public health concern. It affects a broad range of…

Date: 2025-09-08

Serum neurofilament light chain levels in myasthenia gravis patients with and without symptoms

Abstract: This study aimed to investigate serum neurofilament light chain (sNFL) levels in patients with myasthenia gravis (MG) and explore its potential as a biomarker for…

Date: 2025-09-08

Global and Chinese trends in acute myeloid leukemia burden (1990–2021): a comprehensive analysis based on the GBD study

Abstract: Acute myeloid leukemia (AML) poses a significant global health burden. This study evaluates long-term trends in AML burden from 1990 to 2021, focusing on global and…

Date: 2025-09-05

Sex-specific associations of the controlling nutritional status score with diabetic kidney disease among Chinese individuals: a retrospective cross-sectional study

Abstract: Recognizing the crucial role of nutritional status in the advancement of diabetic complications, this investigation aimed to evaluate sex-specific disparities concerning…

Date: 2025-09-05