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Spectrum of gynecologic malignancies in Northeastern Nigeria

Abstract: Background: The burden of female genital tract cancers in low—and middle-income countries (LIMC) is not yet well investigated. Although available studies are few, they…

Date: 2025-03-18

Identification of prognostic subtypes and the role of FXYD6 in ovarian cancer through multi-omics clustering

Abstract: Background: Ovarian cancer (OC), as a malignant tumor that seriously endangers the lives and health of women, is renowned for its complex tumor heterogeneity.…

Date: 2025-03-18

Identification and validation of endoplasmic reticulum stress-related diagnostic biomarkers for type 1 diabetic cardiomyopathy based on bioinformatics and machine learning

Abstract: Background: Diabetic cardiomyopathy (DC) is a serious complication in patients with type 1 diabetes mellitus and has become a growing public health problem worldwide.…

Date: 2025-03-18

Enhancing ophthalmology students’ awareness of retinitis pigmentosa: assessing the efficacy of ChatGPT in AI-assisted teaching of rare diseases—a quasi-experimental study

Abstract: Background: Retinitis pigmentosa (RP) is a rare retinal dystrophy often underrepresented in ophthalmology education. Despite advancements in diagnostics and treatments…

Date: 2025-03-18

Invivo and in vitro analyses of surface whitening in hydrophobic trifocal intraocular lenses

Abstract: Introduction: Transparency loss due to the whitening of trifocal hydrophobic intraocular lenses (IOLs) is a rare but poorly understood phenomenon. This study…

Date: 2025-03-18

A novel grid-assisted pie-crusting technique for achieving soft tissue balance in total knee arthroplasty

Abstract: Background: To evaluate the effectiveness of a novel grid-based pie-crusting technique for soft tissue release at different locations of the medial collateral ligament…

Date: 2025-03-18

Association between plain water intake and the risk of osteoporosis among middle-aged and elderly people in the United States: a cross-sectional study

Abstract: Background: The connection between plain water intake (PWI) and osteoporosis risk is still unclear. The investigation aimed to identify the relationship between PWI and…

Date: 2025-03-18

Tumour necrosis factor-? induces macromolecule translocation in HIV-derived duodenal organoids

Abstract: Background: Disease progression from human immunodeficiency virus (HIV) infection to acquired immunodeficiency syndrome (AIDS) is marked by chronic immune activation,…

Date: 2025-03-18

Prevalence and incidence of multiple sclerosis in Bulgaria

Abstract: Background: Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune, demyelinating and neurodegenerative disease of the central nervous system that primarily…

Date: 2025-03-18

Prediction model for severe autoimmune encephalitis: a tool for risk assessment and individualized treatment guidance

Abstract: Background: Severe autoimmune encephalitis (AE) can cause significant neurological deficits, status epilepticus, status dystonicus, and even death, which can be…

Date: 2025-03-18