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Efficacy and safety of Lemborexant in treating adult patients with insomnia in China: a single-center, retrospective observational study

Abstract: Background: Except for one case report, there has been no published study of Lemborexant treatment for patients with insomnia in China. This study investigated efficacy…

Date: 2025-03-14

Investigating the risks of late preterm and term neonatal morbidity across clinical subtypes of intrahepatic cholestasis of pregnancy

Abstract: Background: This investigation assesses the perinatal risks associated with different clinical subtypes of intrahepatic cholestasis of pregnancy (ICP) based on clinical…

Date: 2025-03-14

Targeting stemness pathways modulates macrophage polarization and reprograms the tumor microenvironment

Abstract: Introduction: The tumor microenvironment plays a pivotal role in cancer progression and therapeutic resistance, with tumor-associated macrophages significantly…

Date: 2025-03-14

Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia

Abstract: Introduction: Patients with acute myeloid leukemia (AML) often carry the same gene mutations. Neoantigens encoded by these mutations are attractive targets for…

Date: 2025-03-13

Neural markers of methylphenidate response in children with attention deficit hyperactivity disorder and the impact on executive function

Abstract: Background: Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. A core…

Date: 2025-03-13

Utilization of lymph node elastography in the axillary staging of breast cancer

Abstract: Background: The differential diagnosis of lymphadenopathy is an important determinant of prognosis in patients with breast cancer (BC). Invasive, fine needle aspiration…

Date: 2025-03-13

Explainable machine learning model and nomogram for predicting the efficacy of Traditional Chinese Medicine in treating Long COVID: a retrospective study

Abstract: Introduction: Long COVID significantly affects patients' quality of life, yet no standardized treatment has been established. Traditional Chinese Medicine (TCM) presents…

Date: 2025-03-13

Assessing housing and basic services access for internally displaced persons in conflict-affected Gaza Strip: a mixed-methods study

Abstract: Background: The Gaza Strip’s protracted conflict has created a severe humanitarian crisis, leaving internally displaced persons (IDPs) with limited access to adequate…

Date: 2025-03-13