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Effect of ultrasound-guided scalp nerve block on hemodynamics and postoperative agitation in hypertensive cerebral hemorrhage craniotomy patients: a prospective randomized controlled study

Abstract: This study aims to investigate the impact of dexmedetomidine combined with ropivacaine scalp nerve block (SNB) on analgesic effects in patients undergoing craniotomy for…

Date: 2026-01-14

Intraoperative hypotension trajectories and their predictive value for major postoperative complications: a retrospective cohort study

Abstract: Intraoperative hypotension (IOH) is a common hemodynamic disturbance during major non-cardiac surgery, yet the prognostic significance of different temporal blood…

Date: 2026-01-14

Dual-filter IPL vs. LED phototherapy combined with systemic therapy for moderate-to-severe acne in Asian patients

Abstract: Intense pulsed light (IPL) is a promising treatment method for acne vulgaris. However, no studies have directly compared IPL with light-emitting diode (LED) phototherapy…

Date: 2026-01-13

The efficacy of red and blue light-emitting diode phototherapy combined with oral minocycline for acne conglobata: a retrospective cohort study

Abstract: Acne conglobata (AC) is a severe inflammatory skin condition with limited therapeutic options that can provide rapid and sustained remission. This retrospective cohort…

Date: 2026-01-12

Immune checkpoint inhibitor-related Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective analysis of 21 cases

Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening severe cutaneous adverse reactions (SCARs) increasingly linked to…

Date: 2026-01-12

Comparative safety profiles of baricitinib and tofacitinib in the treatment of adult alopecia areata: a pharmacovigilance study based on the FAERS database

Abstract: To provide a comparative overview of the post-marketing safety patterns of baricitinib and tofacitinib used for the treatment of adult alopecia areata (AA) by analyzing…

Date: 2026-01-12

Safety profile of vunakizumab in elderly patients with moderate-to-severe plaque psoriasis: a post-hoc analysis

Abstract: Elderly patients with moderate-to-severe plaque psoriasis are vulnerable to adverse events (AEs), which raise safety concerns in their management. This post-hoc analysis…

Date: 2026-01-12

Clinical and laboratory characteristics of hidradenitis suppurativa in a Chinese cohort: a retrospective analysis of 197 cases

Abstract: The clinical and laboratory characteristics of hidradenitis suppurativa (HS), particularly indicators related to disease severity, remain inadequately explored in Asian…

Date: 2026-01-12

The safety of high dose continuous propofol infusion in the pediatric intensive care unit at an academic medical center

Abstract: Adequate sedation is crucial in the care of critically ill children. Propofol, known for its rapid onset, reliable patient response, and short duration of action, offers…

Date: 2026-01-12

Deep learning-based optic nerve diameter sheath characterization and structure quantification on transorbital ultrasound images

Abstract: Optic nerve quantification plays a pivotal role as a biomarker in the non-invasive assessment of elevated intracranial pressure and other neuro-ophthalmic conditions.…

Date: 2026-01-12