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Management of intermediate high-risk pulmonary embolism: a single-center retrospective study

Abstract: Approximately 25% of PE cases are intermediate-risk, with mortality rates between 5% and 25%. Management strategies for intermediate-risk PE remain inconsistent. This…

Date: 2025-08-29

ISI matsuda as a potential predictor of metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus

Abstract: This study aimed to determine the most efficacious insulin resistance (IR) indices to predict metabolic dysfunction-associated steatotic liver disease (MASLD) in…

Date: 2025-08-29

Exercise training improves metabolic and circulatory function in COPD patients with NAFLD: evidence from clinical and molecular profiling

Abstract: Non-alcoholic fatty liver disease (NAFLD) and chronic obstructive pulmonary disease (COPD) are frequently comorbid, affecting up to 41% of COPD patients. Both conditions…

Date: 2025-08-29

Differential expression and correlation analysis of whole transcriptome for type 2 diabetes mellitus

Abstract: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that accounts for 90% or more of all diabetes cases and contributes to the global public health burden.…

Date: 2025-08-29

The association between obstructive sleep apnoea and diabetic peripheral neuropathy in subjects with type 2 diabetes

Abstract: This study aimed to examine the association between obstructive sleep apnoea (OSA) and diabetic peripheral neuropathy (DPN) in subjects with type 2 diabetes mellitus…

Date: 2025-08-29

Knowledge gaps about the diagnosis and treatment of hypothyroidism: an international patient survey

Abstract: Over-diagnosis and over-treatment of hypothyroidism is a growing concern. The role of patient knowledge has not been previously investigated. The aim was to explore…

Date: 2025-08-29

Association of leukocyte telomere length and HbA1c with post-COVID-19 syndrome in type 2 diabetes: a cross-sectional pilot study

Abstract: Leukocyte telomere length is considered a promising prognostic marker associated with COVID-19 severity, adverse outcomes (hospital admission, need for critical care,…

Date: 2025-08-29

Short-term longitudinal clinical, biochemical, and quality of life outcomes of medical or surgical therapy in unilateral primary aldosteronism

Abstract: Unilateral primary aldosteronism (uPA) is a surgically curable form of hypertension, frequently associated with resistant hypertension and cerebro-cardiovascular…

Date: 2025-08-29

A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

Abstract: Acute promyelocytic leukemia (APL) is classically driven by the PML-RARA fusion oncogene and characterized by a maturation arrest of myeloid precursors. Variant APL…

Date: 2025-08-29

Digital biomarkers as predictors of brain injury in neonatal encephalopathy

Abstract: Neonatal encephalopathy (NE) is a significant cause of neurodevelopmental impairment, with therapeutic hypothermia (TH) being the current standard of care for mitigating…

Date: 2025-08-29