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A population-based study of social demographic factors, associated diseases, and herpes zoster ophthalmicus in Taiwan

Abstract: Introduction: Herpes zoster ophthalmicus (HZO) occurs due to the reactivation of latent varicella-zoster virus (VZV) and is characterized by the involvement of the…

Date: 2025-03-06

Systemic inflammatory response index as a novel biomarker for age-related macular degeneration: a cross-sectional study from NHANES (2005–2008)

Abstract: Background: Chronic low-grade systemic inflammation plays a significant role in age-related macular degeneration (AMD) pathogenesis. The systemic inflammatory response…

Date: 2025-03-06

Microglia-derived CXCL2 induced neuronal ferroptosis via CXCR2/Jun axis in sepsis-associated encephalopathy

Abstract: Background: Neuronal ferroptosis is a characteristic pathological change of sepsis-associated encephalopathy (SAE), which can be induced by activated microglia. CXCL2 is…

Date: 2025-03-06

Post-stem cell transplant maintenance for pediatric acute leukemias: insights from a Brazilian institution with a Latin American perspective

Abstract: Introduction: In resource-limited countries, access to advanced therapies like CAR T-cell therapy is often unattainable. Clinical trials face challenges, with pediatric…

Date: 2025-03-05

De novo abnormalities identified by fluorescence in situ hybridization during follow-up confer poor prognosis in Chinese multiple myeloma

Abstract: Background: Although there is evolving consensus to re-evaluate cytogenetic features during follow-up in multiple myeloma (MM), longitudinal studies on cytogenetic…

Date: 2025-03-05

Deep learning-based analysis of 12-lead electrocardiograms in school-age children: a proof of concept study

Abstract: Introduction: The diagnostic performance of automated analysis of electrocardiograms for screening children with pediatric heart diseases at risk of sudden cardiac death…

Date: 2025-03-05

Extracellular microvesicles from patients with Rheumatoid arthritis promote dendritic cell activation in vitro

Abstract: Introduction: Rheumatoid Arthritis (RA) is a systemic autoimmune disease characterized by chronic synovial inflammation affecting diarthrodial joints, with cartilage…

Date: 2025-03-05

Association between maternal emotion socialization and emotion regulation in early adolescents with elevated internalizing symptoms: insights from multi-informant discrepancies

Abstract: Introduction: Although the relationship between parental emotion socialization and emotional competence, including emotion regulation, in children and adolescents has…

Date: 2025-03-05

Self-reported hypoglycemia and associated factors among patients living with T1D s at University of Gondar Comprehensive Specialized Hospital, Northwest, Ethiopia: a cross-sectional study

Abstract: Background: Hypoglycemia is a major public health problem that negatively influences blood glucose control in the treatment of type 1 diabetes. It has more severe…

Date: 2025-03-05

Colorectal lymph node harvest in cancer surgery, adequacy and treatment implication: a 5-year retrospective analysis from a tertiary hospital in Ethiopia

Abstract: Introduction: Colorectal cancer is one of the common malignancies, and obtaining sufficient lymph nodes after surgeries is critical for staging and subsequent treatment…

Date: 2025-03-05