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Research Articles Search

Showing 230 of 147,163 result(s)
Benralizumab for adults with rare and off-label eosinophilic disorders: a 52-week prospective, single-center study

Abstract: Rare eosinophilic disorders are challenging to manage due to their heterogeneity and lack of targeted therapies. Benralizumab, an anti-IL-5 receptor monoclonal antibody…

Date: 2025-10-29

Complete cross strain protection against congenital cytomegalovirus infection requires a vaccine encoding key antibody (gB) and T-cell (immediate early 1 protein) viral antigens

Abstract: Cytomegalovirus is a leading cause of congenital disease, and multiple strains enable congenital CMV (cCMV) from both primary and non-primary infections. Therefore, a…

Date: 2025-10-29

Proteins linked to type II interferon response in Sjögren’s disease: novel indicators for disease monitoring and predicting treatment response to leflunomide and hydroxychloroquine combination therapy

Abstract: To identify biomarkers and endotypes predictive of treatment response, monitor disease activity, and explore pathways associated with the clinical efficacy of…

Date: 2025-10-29

TNF-?-mediated downregulation of CD36 and phagocytic impairment of alveolar macrophages via upregulation of ADAM17 in asthma

Abstract: Alveolar macrophages (AMs) are specialized phagocytes in the airways that play a crucial role in maintaining bronchoalveolar homeostasis through phagocytosis, the…

Date: 2025-10-29

Real-world diagnostic value of integrating oral and ocular dryness testing in suspected Sjögren’s disease

Abstract: Sjögren’s disease is an autoimmune condition requiring a systemic evaluation that integrates serologic, histopathologic, and glandular assessments for diagnosis. Current…

Date: 2025-10-29

Mast cells are essential in the development of exposure-associated exercise-induced bronchoconstriction in a mouse model

Abstract: Cold air and air pollution are known triggers to induce symptoms in exercise-induced bronchoconstriction (EIB). Mast cells are hypothesized to be a key player in the…

Date: 2025-10-29

Combination of CRP and miRNA signature as a potential diagnostic strategy for Kawasaki disease

Abstract: Kawasaki disease is the leading cause of acquired heart disease in children, yet timely diagnosis remains difficult due to overlapping symptoms with other febrile…

Date: 2025-10-29

Associations of sleep disturbances in systemic lupus erythematosus with physical and psychological outcomes: a cross-sectional latent profile analysis

Abstract: Patients with systemic lupus erythematosus (SLE) frequently experience poor sleep quality. This cross-sectional study aimed to identify distinct sleep disturbance…

Date: 2025-10-29

Plasma exosomal lncRNA-related signatures define molecular subtypes and predict survival and treatment response in hepatocellular carcinoma

Abstract: Hepatocellular carcinoma (HCC) faces challenges in early diagnosis, prognosis, and treatment stratification due to molecular heterogeneity. This study aimed to establish…

Date: 2025-10-29

Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NF?B and NFAT pathways

Abstract: Arnica montana L. (Arnica) has a long history of use in treating inflammation and soft tissue injury, yet its immunomodulatory mechanisms remain largely unexplored. In…

Date: 2025-10-29