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The crossroads of inflammation and nutrition: predicting neoadjuvant immunochemotherapy efficacy in esophageal squamous cell carcinoma patients

Abstract: Neoadjuvant immunochemotherapy (nICT) improves outcomes in esophageal squamous cell carcinoma (ESCC); however, patient response heterogeneity limits its clinical…

Date: 2025-11-20

Evaluation of AI-enhanced tele-ECG response time and diagnosis in acute chest pain patients

Abstract: The impact of artificial intelligence in improving Tele-ECG response times and diagnostic accuracy among emergency patients experiencing acute chest pain remains…

Date: 2025-11-20

R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint

Abstract: R3HDM4, or R3H domain containing 4, is a gene with uncertain functions but is frequently investigated for its potential cellular roles and associations with various…

Date: 2025-11-19

Dosimetric parameter determination of a carbon-nanotube based miniature x-ray tube for HDR brachytherapy

Abstract: This study aims to determine key dosimetric parameters of a vacuum-sealed miniature X-ray tube (mXT) equipped with a carbon nanotube field emitter for application in HDR…

Date: 2025-11-19

Establishment and validation of a prognostic model for nasopharyngeal carcinoma patients based on partial response rates

Abstract: This study aims to investigate the impact of varying rates of partial response (PR) on survival outcomes in nasopharyngeal carcinoma (NPC) patients following induction…

Date: 2025-11-19

Oligocentric Castleman disease: clinical characteristics and surgical outcomes from a single-centre retrospective study

Abstract: Oligocentric Castleman Disease (OCD), a distinct subtype of Castleman Disease (CD) intermediate between Unicentric (UCD) and idiopathic Multicentric (iMCD) forms,…

Date: 2025-11-19

Pan-cancer landscape of UBD/FAT10 and experimental validation in esophageal carcinoma

Abstract: To comprehensively characterize the pan-cancer roles of Ubiquitin D (UBD/FAT10) in tumorigenesis, immune regulation, and therapeutic response through integrative…

Date: 2025-11-19

The prognostic value of pretreatment inflammatory and nutrition-related indices in patients with cardia cancer

Abstract: To evaluate the prognostic significance of inflammatory and nutrition-related indexes in patients with cardia cancer prior to treatment. A total of 229 patients with…

Date: 2025-11-19

CD20+ and CD204+ exhibit distinct prognostic associations in thymic epithelial tumors

Abstract: Thymic epithelial tumors (TETs), encompassing thymomas and thymic carcinomas, are rare malignancies originating from thymic epithelial cells. This study aimed to…

Date: 2025-11-18

First-line immune checkpoint inhibitors combined with chemotherapy in advanced large-cell neuroendocrine carcinoma of the lung: a real-world retrospective study

Abstract: Large-cell neuroendocrine carcinoma of the lung (LCNEC) shares clinicopathological features with both small cell lung cancer (SCLC) and non-small cell lung cancer…

Date: 2025-11-18