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Enhancing prognosis in multiple myeloma bone disease: insights from a retrospective analysis of surgical interventions

Abstract: Background: Multiple myeloma (MM) is a hematological malignancy characterized by bone marrow infiltration and osteolytic tumor formation. Despite advancements in the…

Date: 2024-12-19

Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer

Abstract: Introduction: Despite the established influence of gut bacteria, the role of the gut virome in modulating colorectal cancer (CRC) patient chemotherapy response remains…

Date: 2024-12-19

Impaired sensitivity to thyroid hormone is associated with developing non-alcoholic fatty liver disease in euthyroid diabetic subjects

Abstract: Background and aims: Acquired resistance to thyroid hormone appears to exist in the general population. We aimed to evaluate the association between indices of thyroid…

Date: 2024-12-18

The mediating role of self-efficacy in the relationship between health literacy, health status and psychological well-being among German trainees and students in nursing

Abstract: Introduction: Health literacy is considered a determinant of several health-related behaviors and outcomes. Health literacy can be seen as a particularly relevant…

Date: 2024-12-18

Melanoma toolkit for early detection for primary care clinicians: a 1-year follow-up on outcomes

Abstract: Introduction: Primary care providers or clinicians (PCPs) have the potential to assist dermatologists in screening patients at risk for skin cancer, but require training…

Date: 2024-12-18

Spatial heterogeneity and predictors of stunting among under five children in Mozambique: a geographically weighted regression

Abstract: Introduction: Childhood stunting, a major public health concern in many developing countries, is associated with impaired physical and cognitive development, increased…

Date: 2024-12-18

Hypoxic conditions affect transcriptome of endometrial stromal cells in endometriosis and promote TGFBI axis

Abstract: Background: Endometriosis is characterized by the ectopic growth of endometrial-like cells, causing chronic pelvic pain, adhesions and impaired fertility in women of…

Date: 2024-12-18

Validation of the World Health Organization’s Disability Assessment Schedule 2.0 for children with mental disorders in specialized health-care services

Abstract: Introduction: Mental disorders are highly prevalent among children, yet access to timely and effective treatment remains limited. Untreated or poorly managed mental…

Date: 2024-12-18