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Evaluating the 3-month post-intervention impact of a supportive text message program on mental health outcomes during the 2023 wildfires in Alberta and Nova Scotia, Canada

Abstract: Background: Individuals exposed to wildfires are at risk of developing adverse mental health conditions in the months following the event. Receiving supportive text…

Date: 2024-12-18

Association between waist-to-height ratio and osteoporosis in the National Health and Nutrition Examination Survey: a cross-sectional study

Abstract: Background: The link between waist-to-height ratio (WHtR) and osteoporosis (OP) remains a contentious issue in the field of medical research. Currently, the available…

Date: 2024-12-18

Association between CLOCK gene polymorphisms with circadian rhythm, chrononutrition, dietary intake, and metabolic parameters in adolescents

Abstract: Introduction: Circadian Locomotor Output Cycles Kaput (CLOCK) is one of the transcription factors from the positive end of the molecular clock and regulates biological…

Date: 2024-12-18

Establishment and evaluation of a carotid artery dissection model in rats

Abstract: Background: Given the lack of models for carotid artery dissections (CAD), we aim to investigate effects of beta-aminopropionitrile (BAPN) combined with physical damage…

Date: 2024-12-18

Clinical characteristics of adrenal crisis in 371 adult patients with glucocorticoid-induced adrenal insufficiency

Abstract: Background: Glucocorticoid-induced adrenal insufficiency (GIAI) is a hypothalamic-pituitary-adrenal (HPA) axis dysfunction caused by long-term use of exogenous steroids.…

Date: 2024-12-17

Correlations of the triglyceride?glucose index and modified indices with arterial stiffness in overweight or obese adults

Abstract: Background: Insulin resistance (IR) contributes substantially to the development of cardiovascular disease (CVD) and metabolic disorders, particularly obesity. The…

Date: 2024-12-17

Sclerostin and OPG/RANK-L system take part in bone remodeling in patients with acromegaly

Abstract: Introduction: Acromegaly is a disease characterized by enhanced bone turnover with persistently high vertebral fracture risk. Sclerostin is a glycoprotein, which acts as…

Date: 2024-12-17

Predicting grip strength-related frailty in middle-aged and older Chinese adults using interpretable machine learning models: a prospective cohort study

Abstract: Introduction: Frailty is an emerging global health burden, and there is no consensus on the precise prediction of frailty. We aimed to explore the association between…

Date: 2024-12-17

Targeting liver cancer stem cells: the prognostic significance of MRPL17 in immunotherapy response

Abstract: Background: Liver hepatocellular carcinoma (LIHC) ranks as the foremost cause of cancer-related deaths worldwide, and its early detection poses considerable challenges.…

Date: 2024-12-17

Machine learning-based selection of immune cell markers in osteosarcoma: prognostic determination and validation of CLK1 in disease progression

Abstract: Introduction: Osteosarcoma (OS) is a malignancy of the bone that mainly afflicts younger individuals. Despite existing treatment approaches, patients with metastatic or…

Date: 2024-12-17