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Research Articles Search

Showing 260 of 147,163 result(s)
An analysis of the distribution of bone and soft tissue sarcoma diagnoses and their disparities in Southwest Germany: a multicenter approach

Abstract: Sarcoma is a rare and highly heterogeneous family of mesenchymal tumors. The experience and interdisciplinary approach of specialized high-volume sarcoma centers has a…

Date: 2025-10-29

Residual pattern of primary tumor and lymph node in ESCC treated with nCRT with or without pembrolizumab: an analysis from a prospective cohort

Abstract: Neoadjuvant chemoradiotherapy (nCRT) is recommended as the standard of care for locally advanced esophageal squamous cell carcinoma (ESCC). Adding immunotherapy to nCRT…

Date: 2025-10-29

Comparative impact of supine vs prone positioning on dose distribution, acute toxicity, and setup error in postoperative radiotherapy for cervical cancer: a multidimensional propensity-matched cohort study

Abstract: Postoperative radiotherapy is standard for high-risk cervical cancer, but acute toxicities—particularly gastrointestinal and hematologic—remain clinically relevant.…

Date: 2025-10-29

Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China

Abstract: False negatives in colorectal cancer (CRC) screening remained a widespread concern, particularly given the notable incidence of false negative results from fecal…

Date: 2025-10-29

Establishment and comparison of three fear of progression risk prediction models for gynecological malignancies patients based on machine learning

Abstract: This study applied the Society Ecosystems Theory to investigate Fear of Progression (FoP) prevalence and predictors in gynecological malignancy patients. By constructing…

Date: 2025-10-29

Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study

Abstract: Early stage breast cancer treated with adjuvant radiotherapy with two different techniques, tomotherapy (TOMO) and intensity-modulated radiation therapy (IMRT), and…

Date: 2025-10-29

MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis

Abstract: Major Facilitator Superfamily Domain-containing 12 (MFSD12) has emerged as a critical transmembrane protein with increasingly recognized roles in various cancers. The…

Date: 2025-10-29

Prognostic value of patient-reported outcomes for survival in patients with advanced lung cancer receiving immune checkpoint inhibitors

Abstract: There is potential clinical utility in using patient-reported outcomes (PROs) to predict survival in patients with advanced non-small cell lung cancer. We assessed the…

Date: 2025-10-29

The 41BB-agonist potentiates the therapeutic efficacy of a combined irreversible electroporation ablation treatment of lung cancer by promoting unexpected CD8 + CD103 + cDC1 and tissue-resident memory T cell responses

Abstract: Irreversible electroporation (IRE) is a relatively new, non-thermal ablation technology for cancer treatment that requires further investigation to optimize its…

Date: 2025-10-29

Global, regional, and national epidemiology and risk factors of geriatric digestive system cancers from 1990 to 2021

Abstract: Using Global Burden of Disease (GBD) 2021 data, we analyzed incidence, mortality, disability-adjusted life years (DALYs), and risk factors for six geriatric digestive…

Date: 2025-10-29