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Prediction model and significance of myocardial injury induced by fluorouracil combined with platinum-based chemotherapy in advanced gastric cancer based on baseline data and inflammation-nutrition-atherosclerosis factors

Abstract: To develop and evaluate a predictive model for myocardial injury in patients with advanced gastric cancer treated with fluorouracil plus platinum-based chemotherapy,…

Date: 2025-11-18

How to predict progression-free survival in patients with grade 2 IDH-mutated diffuse gliomas after surgery: a long-term follow-up analysis

Abstract: Available prognostic scores for adult-type diffuse glioma with isocitrate dehydrogenase (IDH) mutant were validated before the evaluation of biomolecular features. The…

Date: 2025-11-18

Influencing factors of emotional well-being in Chinese patients with gastroenteric tumours: the role of mindfulness practice, social support and patient-centred communication

Abstract: This study aimed to explore the factors influencing the emotional well-being of patients with gastroenteric tumours and to examine the mediating roles of beliefs about…

Date: 2025-11-17

Exploring motivations and barriers in prostate cancer screening: lessons from a volunteer-based MRI screening study

Abstract: Prostate cancer remains a significant public health challenge, an early detection with prostate-specific antigen (PSA) testing and biparametric MRI (bpMRI) can improve…

Date: 2025-11-17

Real-world data analysis of adjuvant capecitabine for triple-negative breast cancer after neoadjuvant chemotherapy

Abstract: Evaluate real-world outcomes in three cohorts of patients with early-stage triple-negative breast cancer (TNBC) treated with neoadjuvant chemotherapy (NAC): (1) patients…

Date: 2025-11-17

Impact of clinical and dosimetric factors on severe oral mucositis in head and neck cancer: insights from a phase II clinical trial

Abstract: Oral mucositis (OM) is the most common acute treatment-limiting adverse effect in patients with head and neck cancer (HNC), particularly following concomitant…

Date: 2025-11-17

Oxaliplatin versus irinotecan as first-line therapy in metastatic colorectal cancer with prior adjuvant treatment: a retrospective study on efficacy, sequential therapy, and the impact of thrombocytopenia

Abstract: The comparative efficacy of oxaliplatin versus irinotecan as first-line therapy in mCRC patients with prior adjuvant treatment remains unclear. To compare the efficacy…

Date: 2025-11-17

Clinical comparison of radiofrequency ablation and surgical resection in treating pulmonar metastasis of hepatoblastoma

Abstract: To explore the efficacy variances between radiofrequency ablation and traditional surgical resection in treating pulmonary metastasis of hepatoblastoma in children, and…

Date: 2025-11-17

Effectiveness of an improved fall risk assessment form combined with obstacle physical activity testing in preventing falls in older adults hospitalized patients

Abstract: This study aimed to evaluate the effectiveness of personalized preventive interventions guided by an improved Risk Assessment Form and an obstacle physical activity test…

Date: 2025-10-28

Association between C-reactive protein-triglyceride glucose index and all-cause mortality and premature death: a joint analysis based on case data from the Central Hospital of Shaoyang and CHARLS database

Abstract: This study systematically investigates the relationship between C-reactive protein-triglyceride glucose index (CTI) and the risks of all-cause and premature mortality. A…

Date: 2025-10-28