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Neuroendoscopic hematoma evacuation vs. craniotomy in hypertensive intracerebral hemorrhage: a retrospective comparative study on surgical efficiency and long-term functional outcomes

Abstract: To investigate the impact of neuroendoscopic surgery on surgical efficiency and long-term functional outcomes in patients with hypertensive intracerebral hemorrhage…

Date: 2025-10-27

Novel insights and clinical perception of the patients with acute leukemia transferred to ICU: a multi-center retrospective study spanning 10?years

Abstract: Intensive care unit (ICU) is a professional and special ward for the treatment of various critical and severe diseases in clinical medical institutions, which is an…

Date: 2025-10-27

MiR-668-5p targets ZNRF3, an E3 ubiquitin ligase to enhance osteoblast function and alleviate senescence in doxorubicin-induced age-related bone loss

Abstract: Aging is a complex biological phenomenon that drives the progression of numerous chronic conditions, including osteoporosis, which is characterized by bone loss and…

Date: 2025-10-27

Bilateral breast nodules as an unusual manifestation of 17?-hydroxylase/17,20-lyase deficiency

Abstract: 17?-hydroxylase/17,20-lyase deficiency (17-OHD) typically presents with sexual infantilism, hypertension, and hypokalemia. However, phenotypic variability, particularly…

Date: 2025-10-27

The relationship between copper intake and chronic kidney disease/diabetic kidney disease: insights from NHANES data (2011-2018)

Abstract: The connection between copper consumption and chronic kidney disease (CKD), as well as diabetic kidney disease (DKD), is still unclear. This research seeks to explore…

Date: 2025-10-27

Diagnostic performance of a radiological Fagotti score assessed on diffusion-weighted magnetic resonance imaging for predicting tumor resectability in ovarian cancer patients: a feasibility study

Abstract: In ovarian cancer, the correct selection of patients for cytoreductive surgery is of great importance. The aim of this study was to evaluate the diagnostic performance…

Date: 2025-10-27

Investigating the causal role of cellular senescence-related genes in preeclampsia: a multi-omics Mendelian randomization study with differential expression analysis

Abstract: The causal role of cellular senescence in preeclampsia pathogenesis is not fully established. This study aimed to systematically prioritize key senescence-related genes…

Date: 2025-10-27

Perinatal outcomes of spontaneous single fetal death in monochorionic twin pregnancies: a single-center retrospective study

Abstract: The aim of this study was to investigate the perinatal outcomes of surviving co-twins after spontaneous single intrauterine fetal death (sIUFD) in monochorionic (MC)…

Date: 2025-10-27

Predictive model of sperm DNA fragmentation in infertile men based on lifestyle factors

Abstract: This study aimed to investigate the influence of lifestyle factors on the sperm DNA fragmentation index (DFI) in infertile men, and to develop and validate a predictive…

Date: 2025-10-27

Temperament correlates of stigma resistance among patients with mood disorders: a cross-sectional study

Abstract: In the realm of mental health, stigma presents a barrier to well-being and social acceptance. However, amidst societal prejudices, stigma resistance emerges as a vital…

Date: 2025-10-27