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Research Articles Search

Showing 290 of 147,163 result(s)
Global burden of early-onset pancreatic cancer attributable to metabolic risks from 1990 to 2021, and projections to 2030

Abstract: This study, based on the Global Burden of Disease (GBD) 2021 data, systematically analyzed the changes in the disease burden of early-onset pancreatic cancer (EOPC)…

Date: 2025-10-29

Metabolic syndrome worsens sarcopenia and reduces nutritional therapy benefits in advanced gastric cancer

Abstract: Emerging evidence suggests metabolic syndrome (MetS) exacerbates sarcopenia progression and compromises nutritional interventions, yet its dual role as both etiological…

Date: 2025-10-29

Cost-effectiveness of cadonilimab plus chemotherapy vs chemotherapy alone for advanced gastric cancer: evidence to inform drug pricing in the U.S. and China

Abstract: Cadonilimab, a bispecific antibody targeting programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), was the first agent of its…

Date: 2025-10-29

European experience of patients with HER2-positive advanced/metastatic breast cancer accessing trastuzumab deruxtecan through a named patient program: the EUROPA T-DXd study

Abstract: In January 2021, trastuzumab deruxtecan (T-DXd) received conditional approval in the European Union for the treatment of human epidermal growth factor receptor…

Date: 2025-10-29

Analysis of lymph node recurrence patterns and risk factors in locally advanced esophageal carcinoma following neoadjuvant therapy

Abstract: Although neoadjuvant therapy followed by surgery is the standard treatment for resectable locally advanced esophageal carcinoma, heterogeneity exists in neoadjuvant…

Date: 2025-10-29

Quality of life and pain severity changes over time in patients with breast cancer who were referred for palliative oncology treatment in Indonesia: a hospital-based cohort study

Abstract: Understanding quality of life (QOL) and changes in pain severity over time is important to quantify cancer patients' treatment outcomes. However, this information is…

Date: 2025-10-29

Real-world study of adebrelimab as first-line therapy for extensive-stage small cell lung cancer: a retrospective study

Abstract: Extensive-stage small cell lung cancer (ES-SCLC) has a poor prognosis, with historical median overall survival (OS) of 8–13 months under platinum-etoposide chemotherapy.…

Date: 2025-10-29

Multi-omics profiling reveals the role of 4-ethylbenzoic acid in promoting proliferation and invasion of cervical cancer

Abstract: Cervical cancer (CC) is a global health challenge, ranking fourth among cancers in women. Microbiome–metabolome interactions influence human papillomavirus (HPV)…

Date: 2025-10-29

Association of white blood cell count to hemoglobin ratio with the life quality after laparoscopic surgery in patients with endometriosis

Abstract: Endometriosis (EM) is a common hormone-dependent and chronic inflammatory disease affecting women of reproductive age, characterized by pelvic pain, infertility, and…

Date: 2025-10-29

Chromosome 11q13 amplification as a decision-making biomarker for anti-PD-1 immunotherapy in recurrent or metastatic head and neck squamous cell carcinoma: a prospective cohort study

Abstract: Anti-programmed cell death protein 1 (anti-PD-1) immunotherapy has shown efficacy in recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), but…

Date: 2025-10-29