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Outcomes and toxicities in patients with diffuse-large B cell lymphoma involving the gastrointestinal tract and digestive organs

Abstract: Background: Diffuse large B-cell lymphoma (DLBCL) involving the gastrointestinal (GI) organs is rare, and real-world outcomes after combined modality therapy (CMT) with…

Date: 2024-09-11

Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis

Abstract: Background: Gut microbiota (GM) and metabolic alterations play pivotal roles in lung cancer (LC) development and host genetic variations are known to contribute to LC…

Date: 2024-09-11

The molecular tumor board as a step in cancer patient management: a southern Italian experience

Abstract: Introduction: The management of cancer patients follows a Diagnostic Therapeutic and Care Pathway (PDTA) approach, aimed at achieving the optimal balance between care…

Date: 2024-09-11

The potential of retinoic acid receptors as prognostic biomarkers and therapeutic targets in gastric cancer

Abstract: Background: Gastric cancer is a heterogeneous collection of tumors characterized by low survival rates. All-trans retinoic acid (retinoic-acid) is a clinically useful…

Date: 2024-09-11

CD8 T cells promote heart failure progression in mice with preexisting left ventricular dysfunction

Abstract: Introduction: Even under the standard medical care, patients with left ventricular (LV) failure or heart failure (HF) often progress to pulmonary hypertension and right…

Date: 2024-09-11

Autoantibody profiling of patients with immune checkpoint inhibitor-associated myocarditis: a pilot study

Abstract: Background: Immune checkpoint inhibitor (ICI)-associated myocarditis is a rare, but potentially fatal, immune-related adverse event. Hence, identifying biomarkers is…

Date: 2024-09-11

Effects of interleukin-1 receptor antagonism in women with polycystic ovary syndrome—the FertIL trial

Abstract: Introduction: Chronic low-grade inflammation might contribute to hyperandrogenemia and metabolic complications in polycystic ovary syndrome (PCOS). The proinflammatory…

Date: 2024-09-11

Heart failure biomarkers in revascularized patients with stable coronary heart disease as clinical outcome predictors

Abstract: Introduction: The aim of this study was to investigate serum levels of galectin-3 (Gal-3) and N-terminal pro-brain Natriuretic Peptide (NT-proBNP) in patients with…

Date: 2024-09-11

A comprehensive study of psychological well-being and traditional Chinese medicine constitutions among model workers in Beijing

Abstract: Background: Body constitution is the foundation of Traditional Chinese Medicine (TCM), and model workers consist of a special group of workers within China. This study…

Date: 2024-09-11