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De novo and recurrent post-transplant membranous nephropathy cases show similar rates of concurrent antibody-mediated rejection

Abstract: Background: Membranous nephropathy (MN) can develop post-kidney transplant and is classified as a recurrent disease in patients with a history of MN in the native…

Date: 2024-09-03

Effect of the immune cells and plasma metabolites on rheumatoid arthritis: a mediated mendelian randomization study

Abstract: Background: Increasing evidence indicates a close relationship between alterations in human immune cells and plasma metabolites with Rheumatoid Arthritis (RA). However,…

Date: 2024-09-03

The psychometric properties of the Swahili version of the Primary Care Post Traumatic Stress Disorder screen for DSM-5 among adults in Kenya

Abstract: Background: The psychometric properties of the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) are undocumented in Kenya and sub-Saharan Africa (SSA) at large. This study…

Date: 2024-09-03

The longitudinal study of the relationship between social participation pattern and depression symptoms in frail older adults

Abstract: Background: Mental health challenges are encountered by frail older adults as the population ages. The extant literature is scant regarding the correlation between…

Date: 2024-09-03

A PRDM16-driven signal regulates body composition in testosterone-treated hypogonadal men

Abstract: Background: Testosterone (T) therapy increases lean mass and reduces total body and truncal fat mass in hypogonadal men. However, the underlying molecular mechanisms for…

Date: 2024-09-02

The causal effects of inflammatory and autoimmune skin diseases on thyroid diseases: evidence from Mendelian randomization study

Abstract: Background: To clarify the controversy between inflammatory or autoimmune skin diseases and thyroid diseases, we performed two-sample Mendelian randomization (MR)…

Date: 2024-09-02

Association among biomarkers, phenotypes, and motor milestones in Chinese patients with 5q spinal muscular atrophy types 1–3

Abstract: Background: Biomarkers can be used to assess the severity of spinal muscular atrophy (5q SMA; SMA). Despite their potential, the relationship between biomarkers and…

Date: 2024-09-02