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Deaths in jail: a retrospective analysis of autopsies performed at the Legal Medicine Unit of Pavia (1999-2022)

Abstract: Introduction: The high rate of incarceration, now exceeding 11.5 million people worldwide, has raised concerns about the conditions within penal institutions, such as…

Date: 2024-09-02

Sex differences in the association between chest computed tomography-defined sarcopenia and cardiovascular risk factors among inpatients

Abstract: Background: While sarcopenia has been found to be associated with increased risks of cardiovascular diseases (CVDs), evidence exploring sex-related differences remains…

Date: 2024-09-02

A nomogram model for early recurrence of HBV-related hepatocellular carcinomas after radical hepatectomy

Abstract: Background: To identify the risk factors and construct a predictive model for early recurrence of hepatitis B virus(HBV-)- related hepatocellular carcinomas(HCCs) after…

Date: 2024-09-02

Construction of tissue engineered cornea with skin-derived corneal endothelial-like cell and mechanism research for the cell differentiation

Abstract: Introduction: Corneal endothelial transplantation accounts for most of corneal transplantation for treating corneal diseases, however severe shortage of corneal donors…

Date: 2024-09-02

Retrospective analysis of lithium treatment: examination of blood levels

Abstract: Introduction: Lithium is a key medication for treating various neuropsychiatric disorders, with a narrow therapeutic index and significant drug interactions. Monitoring…

Date: 2024-08-30

Incidence of childhood cancers in the North East geopolitical zone of Nigeria

Abstract: Introduction: Cancers are a major cause of childhood mortality worldwide especially in LMICs where underdiagnoses and lack of quality cancer data hampers effective…

Date: 2024-08-30

Long-term outcomes of transcatheter atrial septal defect closure: a single-center retrospective study

Abstract: Background: Transcatheter atrial septal defect (ASD) closure is the primary approach for treating ASD secundum; however, data on long-term outcomes remain limited. This…

Date: 2024-08-30

Engineered IRES-mediated promoter-free insulin-producing cells reverse hyperglycemia

Abstract: Background: Endogenous insulin supplementation is essential for individuals with type 1 diabetes (T1D). However, current treatments, including pancreas transplantation,…

Date: 2024-08-30

Mitochondrial dysfunction and onset of type 2 diabetes along with its complications: a multi-omics Mendelian randomization and colocalization study

Abstract: Background: Mitochondrial dysfunction plays a crucial role in Type 2 Diabetes Mellitus (T2DM) and its complications. However, the genetic pathophysiology remains under…

Date: 2024-08-30