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Causal relationships between systemic inflammatory cytokines and adhesive capsulitis: a bidirectional Mendelian randomization study

Abstract: Background: Mounting evidence suggests a connection between inflammatory cytokines and adhesive capsulitis (AC). However, the specific systemic inflammatory cytokines…

Date: 2024-06-24

Potential thresholds of critically increased cardiac-related spinal cord motion in degenerative cervical myelopathy

Abstract: Introduction: New diagnostic techniques are a substantial research focus in degenerative cervical myelopathy (DCM). This cross-sectional study determined the…

Date: 2024-06-24

Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation

Abstract: Introduction: The endocannabinoid system (ECS), named after the chemical compounds found in the cannabis plant, is a regulatory network of neurotransmitters, receptors,…

Date: 2024-06-24

The association of composite dietary antioxidant index with periodontitis in NHANES 2009–2014

Abstract: Background: To date, evidence is rare regarding whether and how dietary antioxidants are associated with the risk of periodontitis. This study aimed to investigate the…

Date: 2024-06-24

Changes in tryptophan breakdown associated with response to multimodal treatment in depression

Abstract: Background: Research on depression showed that dysregulations in tryptophan (TRP), kynurenine (KYN), and its KYN pathway metabolites are key aspects in the development…

Date: 2024-06-21

Prevalence and associated factors of premenstrual dysphoric disorder among high school students in Finote Selam town, northwest Ethiopia

Abstract: Background: Premenstrual dysphoric disorder (PMDD) is the most prevalent but neglected psychiatric disorder, with somatic symptoms that are severe enough to markedly…

Date: 2024-06-21

Clinical and structural damage outcomes in axial spondyloarthritis patients receiving NSAIDs or advanced therapies: a description of a real-life cohort

Abstract: Introduction: This study aims to describe the clinical characteristics, disease activity, and structural damage in patients with axial spondyloarthritis (axSpA) who…

Date: 2024-06-20

Yishen Tongbi decoction attenuates inflammation and bone destruction in rheumatoid arthritis by regulating JAK/STAT3/SOCS3 pathway

Abstract: Background: Yishen-Tongbi Decoction (YSTB), a traditional Chinese prescription, has been used to improve syndromes of rheumatoid arthritis (RA) for many years. Previous…

Date: 2024-06-20

Causal relationships between height, screen time, physical activity, sleep and myopia: univariable and multivariable Mendelian randomization

Abstract: Background: This study aims to investigate the independent causal relation between height, screen time, physical activity, sleep and myopia.

Date: 2024-06-20

Efficacy of advanced hybrid closed loop systems in cystic fibrosis related diabetes: a pilot study

Abstract: Background and aims: Cystic fibrosis related diabetes (CFRD) is correlated with worsening of nutritional status and greater deterioration of lung function. The role of…

Date: 2024-06-20