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Iron deficiency anemia and the risk of new-onset tinnitus in female patients: a cohort study

Abstract: Iron deficiency anemia (IDA) may compromise auditory function through cochlear hypoxia and altered hemodynamics; however, longitudinal evidence linking IDA to tinnitus…

Date: 2025-11-28

Associations between COVID-19 impact and subsequent substance use in adolescents with chronic pain

Abstract: The current cross-sectional study retrospectively investigated associations between COVID-19-related factors and subsequent substance use in adolescents with chronic…

Date: 2025-11-28

Real-world efficacy and safety of dupilumab in the treatment of head and neck atopic dermatitis: a retrospective cohort study

Abstract: Head and neck atopic dermatitis (HNAD) is a clinically common subtype of AD. While dupilumab is widely used in AD treatment, its efficacy in HNAD is debatable. This…

Date: 2025-11-27

A composite score of serum cytokines enables early identification of patients at high risk for irAEs under immune checkpoint inhibition

Abstract: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of advanced skin cancers. However, potentially severe and irreversible immune-related adverse events…

Date: 2025-11-27

The influencing factors of postoperative sleep disorders in elderly patients undergoing hip replacement surgery under general anesthesia and the construction and validation of a nomogram prediction model

Abstract: To explore the influencing factors of postoperative sleep disorders in elderly patients undergoing hip replacement (HR) under general anesthesia, and to construct and…

Date: 2025-11-27

Gallic acid alleviates visceral hyperalgesia following maternal separation in mice by inhibiting EphrinB2/EphB2 signaling mediated activation of neurons and glial cells

Abstract: Early life stress (ELS) causes functional gastrointestinal issues linked to visceral hyperalgesia. Activation of spinal neurons and glial cells is key to the development…

Date: 2025-11-27

S-1 maintenance chemotherapy following definitive chemoradiotherapy in high-risk locally advanced nasopharyngeal carcinoma: a propensity score-matched analysis

Abstract: To evaluate the efficacy and safety of S-1 maintenance chemotherapy after definitive chemoradiotherapy in patients with high-risk, locally advanced nasopharyngeal…

Date: 2025-11-26

Serum creatinine-to-cystatin C ratio and 1-year mortality risk in advanced breast cancer patients: a multicenter retrospective cohort study

Abstract: Muscle wasting and sarcopenia in advanced breast cancer correlates with poor outcomes. The serum creatinine-to-cystatin C ratio (CCR) is a potential muscle mass…

Date: 2025-11-26

Single center experience of the impact of artificial intelligence image analysis software on short-term prognosis of non-small cell lung cancer

Abstract: To explore the single center experience of the value of artificial intelligence image analysis software in short-term prognostic assessment of non-small cell lung…

Date: 2025-11-26

Compare the prognosis of pancreatic cancer patients with different treatment modalities and use machine learning methods to build predictive models

Abstract: Pancreatic cancer (PC) is highly refractory to most treatments. Multimodal treatment, combining several types of therapies, is likely to benefit PC patients. However, it…

Date: 2025-11-26