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Association of gut microbiota with lactose intolerance and coeliac disease: a two-sample Mendelian randomization study

Abstract: Background and objectives: Lactose intolerance and coeliac disease are common clinical nutrient malabsorption disorders, with an unclear pathogenesis and limited…

Date: 2024-08-06

Illness-related variables and abnormalities of resting-state brain activity in schizophrenia

Abstract: Background: The development of neuroimaging biomarkers in patients with schizophrenia (SCZ) requires a refined clinical characterization. A limitation of the…

Date: 2024-08-06

Prison healthcare service use and associated factors: a cross sectional study in Northwestern Ethiopia

Abstract: Introduction: Studies on inmates’ Health Care Service (HCS) utilization are scarce globally, infrequent in Ethiopia while findings about the factors associated with HCS…

Date: 2024-08-06

Exploring the genetic and socioeconomic interplay between ADHD and anxiety disorders using Mendelian randomization

Abstract: Background: ADHD and anxiety disorders often co-occur, sharing symptoms and dysfunctions, yet the underlying mechanisms remain elusive.

Date: 2024-08-06

Head circumference growth in children with Autism Spectrum Disorder: trend and clinical correlates in the first five years of life

Abstract: Background: Macrocephaly is described in almost 15% of children with Autism Spectrum Disorder (ASD). Relationships between head growth trajectories and clinical findings…

Date: 2024-08-06

Drug fever—an immune-mediated delayed type hypersensitivity reaction to Vinca alkaloids in pediatric oncology patients, possibly mediated by cysteinyl leukotrienes

Abstract: Background: Drug hypersensitivity reactions are common in pediatric hemato-oncology patients due to multiple factors including immune compromise and pharmacological…

Date: 2024-08-06

Development and validation of a nomogram combining pain score with laboratory indicators for predicting persistent organ failure in acute pancreatitis: a retrospective cohort study

Abstract: Background: Acute pancreatitis is an inflammatory disease that can lead to persistent organ failure (POF), which is associated with increased morbidity and mortality.…

Date: 2024-08-06

Vitamin A supplementation status and associated factors among children aged 6–59?months in Tanzania: a multi-level analysis

Abstract: Background: Vitamin A supplementation every 4–6 months is an economical, rapid, and effective strategy to enhance vitamin A status and minimize child morbidity and…

Date: 2024-08-06

The association between frailty and the risk of mortality in critically ill congestive heart failure patients: findings from the MIMIC-IV database

Abstract: Background: Frailty is a severe, common co-morbidity associated with congestive heart failure (CHF). This retrospective cohort study assesses the association between…

Date: 2024-08-05

Dendritic cells transfected with DNA constructs encoding CCR9, IL-10, and type II collagen demonstrate induction of immunological tolerance in an arthritis model

Abstract: Introduction: Restoring immune tolerance is a promising area of therapy for autoimmune diseases. One method that helps restore immunological tolerance is the approach…

Date: 2024-08-05