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Age-dependent molecular variations in osteosarcoma: implications for precision oncology across pediatric, adolescent, and adult patients

Abstract: Background: Osteosarcoma is a leading subtype of bone tumor affecting adolescents and adults. Comparative molecular characterization among different age groups,…

Date: 2024-05-22

Diastolic and systolic blood pressure and gout: a Mendelian randomization study

Abstract: Background: Although there is solid epidemiological evidence supporting the connection between hypertension and gout, little has been said about the relationship between…

Date: 2024-05-22

Causal associations between platelet count, alcohol consumption, and the risk of liver hepatocellular carcinoma based on a Mendelian randomization study

Abstract: Background and aims: Liver hepatocellular carcinoma (LIHC) exhibits a multifactorial etiology, insidious onset, and a significantly low 5-year survival rate. We aimed to…

Date: 2024-05-22

Secular trends of dental caries and association with nutritional status: a retrospective analysis of 16,199 Chinese students from three successive national surveys from 2010 to 2019

Abstract: Introduction: The prevalence of dental caries (DC) among students in developing countries has increased at an alarming rate, and nutritional status has been shown to be…

Date: 2024-05-22

The outcomes of microvascular decompression for primary trigeminal neuralgia: insights from a single-center experience and technical advancements

Abstract: Background: Microvascular decompression (MVD) remains the primary surgical treatment for trigeminal neuralgia due to its positive postoperative results. This study aims…

Date: 2024-05-22

“We’re one small piece of the puzzle”: evaluating the impact of short-term funding for tier two weight management services

Abstract: Introduction: Overweight and obesity are a global health epidemic and many attempts have been made to address the rising prevalence. In March 2021 the UK government…

Date: 2024-05-22

GastroBot: a Chinese gastrointestinal disease chatbot based on the retrieval-augmented generation

Abstract: Introduction: Large Language Models (LLMs) play a crucial role in clinical information processing, showcasing robust generalization across diverse language tasks.…

Date: 2024-05-22

Immune cell infiltration and prognostic index in cervical cancer: insights from metabolism-related differential genes

Abstract: Background: Cervical cancer remains a significant gynecologic malignancy in both China and the United States, posing a substantial threat to women’s lives and health due…

Date: 2024-05-22