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Expression of pro- and anti-inflammatory cytokines during anti-proprotein convertase subtilisin/kexin type 9 therapy in patients with statin-resistant familial hypercholesterolemia

Abstract: Aim: To evaluate the effect of PCSK9i treatment on pro- and anti-inflammatory cytokines in patients with SR-FH.

Date: 2024-07-18

Trimethylamine N-oxide predicts cardiovascular events in coronary artery disease patients with diabetes mellitus: a prospective cohort study

Abstract: Background: Gut microbiota has significant impact on the cardio-metabolism and inflammation, and is implicated in the pathogenesis and progression of atherosclerosis.…

Date: 2024-07-18

Influence parental- and child-related factors on the acceptance of SARS-CoV-2 test methods in schools and daycare facilities

Abstract: Introduction: Rapid testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections was an essential step in reducing the spread of the virus and…

Date: 2024-07-18

Mendelian randomization analysis reveals a causal relationship between preterm birth and myopia risk

Abstract: Background: Preterm birth has been associated with an increased risk of myopia, but the causal relationship between these two factors remains unclear. Traditional…

Date: 2024-07-18

The causal role of circulating inflammatory markers in osteoporosis: a bidirectional Mendelian randomized study

Abstract: Background: Osteoporosis (OP) associated with aging exerts substantial clinical and fiscal strains on societal structures. An increasing number of research studies have…

Date: 2024-07-18

Comparison of the clinical effect of unilateral transverse process extrapedicular and bilateral transpedicular percutaneous kyphoplasty for thoracolumbar osteoporotic vertebral compression fracture

Abstract: Background: Osteoporosis vertebral compression fractures (OVCF) are common with the aging process. This study aimed to compare the effects of unilateral transverse…

Date: 2024-07-18

Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration

Abstract: Introduction: Chemotherapy, notably docetaxel (Doc), stands as the primary treatment for castration-resistant prostate cancer (CRPC). However, its efficacy is hindered…

Date: 2024-07-18

Associations of neutrophil-percentage-to-albumin ratio level with all-cause mortality and cardiovascular disease-cause mortality among patients with hypertension: evidence from NHANES 1999–2010

Abstract: Background: The associations of neutrophil-percentage-to-albumin ratio (NPAR) level with all-cause and cardiovascular disease (CVD)-cause mortality among patients with…

Date: 2024-07-17