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Research Articles Search

Showing 420 of 147,163 result(s)
Effectiveness and use of evidence-based cardiovascular preventive therapies in type 2 diabetes patients with established or high risk of atherosclerotic cardiovascular disease

Abstract: To explore the association of evidence-based cardiovascular preventive therapies with cardiovascular and renal outcomes in type 2 diabetes (T2DM) patients with…

Date: 2025-10-01

Distinct effects of semaglutide and tirzepatide on metabolic and inflammatory gene expression in brown adipose tissue of mice fed a high-fat, high-fructose diet

Abstract: Brown adipose tissue (BAT) is crucial for overall energy homeostasis as a thermogenic organ with high metabolic activity. While the recruitment of BAT contributes to…

Date: 2025-10-01

Comparison of children with bioinactive growth hormone, small for gestational age, and idiopathic short stature

Abstract: Short stature has many causes, including rare disorders of GH function. Bioinactive growth hormone (GH) refers to a phenotype characterized by immunoreactive but…

Date: 2025-10-01

Genetic and phenotypic heterogeneity of type 2 diabetes across Russian ancestry groups

Abstract: Type 2 diabetes mellitus (T2D) is a highly polygenic disease involving multiple biological pathways. Genetic ancestry may influence the predominant mechanisms driving…

Date: 2025-10-01

Impact of per- and polyfluoroalkyl substances on diabetic kidney disease

Abstract: This study aims to elucidate the mechanistic role of Per- and Polyfluoroalkyl Substances (PFAS) in the pathogenesis and progression of diabetic kidney disease (DKD).…

Date: 2025-10-01

Cross-lagged analysis of burnout and insomnia in older adult patients with diabetes mellitus complicated by hypertension: a 1-year longitudinal follow-up study

Abstract: The aim of this study is to investigate the longitudinal bidirectional relationship between disease management burnout and insomnia symptoms in older adult patients with…

Date: 2025-10-01

Prolactin secreting pituitary neuroendocrine tumors treated by dopamine agonists: predictors of response

Abstract: To date, no specific criteria have been clearly established to predict the response to dopamine agonists (DA), and a universally accepted definition of DA resistance…

Date: 2025-10-01

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

Abstract: Heredity and epigenetic factors contribute to the pathogenesis of neutrophil-cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Cytotoxic T lymphocyte-associated…

Date: 2025-10-01

The relationship between novel inflammatory markers SII, SIRI, MHR, UHR and insulin resistance in patients with type 2 diabetes: based on a retrospective analysis

Abstract: This study aims to investigate the relationship between newly identified inflammatory indicators and IR in patients with T2DM, thereby providing a reference basis for…

Date: 2025-10-01

Urinary iodine concentration and thyroid function in pregnant women with hypertensive disorders

Abstract: Pregnant women are considered a risk group for iodine deficiency, and this condition may be associated with changes in thyroid hormone levels and an increased risk of…

Date: 2025-10-01