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LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis

Abstract: Rosacea is a chronic inflammatory facial dermatosis with incompletely elucidated pathogenesis. LL37 is a key molecular mediator in rosacea development, and mast cells…

Date: 2025-11-26

Recovery time and associated factors of severe acute malnutrition in children aged 0–59?months admitted to referral hospitals in Tanzania: an institution-based prospective cohort study

Abstract: Malnutrition represents a pervasive global health challenge that severely impacts individuals of all ages. In Tanzania, severe acute malnutrition (SAM) is a critical…

Date: 2025-11-26

Spillover effects of military healthcare reform on civilian hospitals in China

Abstract: Military hospitals in China served a dual role, providing substantial healthcare to civilians alongside their primary mission of supporting military personnel. The 2015…

Date: 2025-11-26

Osteocalcin in human breast milk over the course of lactation

Abstract: Breast milk is the best nutrition for newborns. Its composition is dynamic and adapted to the newborn’s individual needs. A variety of bioactive compounds, including…

Date: 2025-11-26

Supporting coach-led dual career guidance for student-athletes: validation of the web-based Japanese version of the dual career competency questionnaire for athletes

Abstract: The concept of a dual career, which emphasizes the integration of athletic and academic pursuits, has become increasingly central to athlete development policies…

Date: 2025-11-26

Research on the impact of traditional Chinese medicine registration innovation-oriented policies and enterprises performance: an empirical analysis based on listed enterprises in China

Abstract: The performance of traditional Chinese medicine (TCM) enterprises is affected by various factors, among which the impact of TCM Registration Innovation-Oriented policies…

Date: 2025-11-26

Prediction model for cognitive impairment in maintenance hemodialysis patients: the role of diabetes

Abstract: The aim of this study was to identify risk factors for cognitive impairment (CI) in maintenance hemodialysis (MHD) patients and to develop a predictive model. A total of…

Date: 2025-11-26

Gastric mucosal change after the eradication of Helicobacter pylori in patients at high risk for gastric cancers

Abstract: Eradication of Helicobacter pylori alone will not eliminate the risk of gastric cancer. There was no conclusive evidence that eradication therapy reduced the incidence…

Date: 2025-11-26

Patterns of response of breast cancer after neoadjuvant chemotherapy according to molecular subtype

Abstract: Neoadjuvant chemotherapy (NACT) is a key component in the treatment of locally advanced breast cancer, with pathologic complete response (pCR) varying by molecular…

Date: 2025-11-26

Machine learning-based prediction of response to Janus kinase inhibitors in patients with rheumatoid arthritis using clinical data

Abstract: Rheumatoid arthritis (RA) is a chronic inflammatory disease with considerable heterogeneity in treatment response, leaving many patients unable to achieve remission or…

Date: 2025-11-26